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德国儿童荨麻疹的护理与医疗费用:药物、医疗及住院服务

[Care and medical costs of urticaria in children in Germany : Drugs, medical and inpatient services].

作者信息

Staubach Petra, Mann Caroline, Hagenström Kristina, Augustin Matthias

机构信息

Klinik und Poliklinik für Dermatologie, Universitätsmedizin Mainz, Mainz, Deutschland.

Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP), Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Deutschland.

出版信息

Dermatologie (Heidelb). 2024 Jul;75(7):554-561. doi: 10.1007/s00105-024-05346-3. Epub 2024 May 22.

Abstract

BACKGROUND

Data on the course of urticaria in children exist, but there is a lack of sound data on patient management to ensure high-quality care.

METHODS

Retrospective secondary data analysis in the field of health care and epidemiology in children with urticaria based on routine data from a German health insurance company (DAK-Gesundheit). Data from insured persons under 18 years of age who were treated as outpatients or inpatients with a diagnosis of urticaria (according to ICD-10 classification) in 2010-2015 were included. The control group consisted of children without a corresponding diagnosis, in order to clarify health economic and care-related differences after adjusting for age and gender.

RESULTS

In 2015, 1904 (1.3%) of 151,248 insured minors had a diagnosis of urticaria. Of the children with urticaria, 70.9% visited at least one physician on an outpatient basis. Of these visits, 70.9% were made to a pediatrician, 52.5% to a general practitioner and 33.0% to a dermatologist; 11% were treated as inpatients. With a total of 151,248 insured persons, 1904 of whom were diagnosed with urticaria, 72.9% of children and adolescents with versus 28.9% without urticaria were treated topically or systemically in 2015, including 10.5% of children with urticaria vs. 2.6% without urticaria received topical therapy and 70.0% with urticaria received systemic therapy vs. 27.5% without urticaria with systemic therapy. The most commonly used oral medications for urticaria were cetirizine (44.2%), prednisolone (9.8%), and dimetindene (2.0%) . Topical methylprednisolone aceponate (49.8%) was prescribed most frequently. The therapy costs for systemic drugs was € 24.00 per patient, while topical drugs cost € 1.58 per patient.

CONCLUSION

The lack of guidelines for the standardization of treatment in children still leads to ambiguities and different treatment concepts among the specialist groups, which must be eliminated in order to enable more efficient therapies. The treatment of chronic urticaria in children and adolescents is mainly carried out by pediatricians, general practitioners and dermatologists. Systemic and topical medications as well as inpatient services are the most important cost factors.

摘要

背景

关于儿童荨麻疹病程的数据已有,但缺乏关于患者管理的可靠数据以确保高质量护理。

方法

基于德国一家健康保险公司(DAK-Gesundheit)的常规数据,对儿童荨麻疹领域的医疗保健和流行病学进行回顾性二次数据分析。纳入2010 - 2015年期间被诊断为荨麻疹(根据国际疾病分类第十版[ICD - 10]分类)的18岁以下门诊或住院参保人员的数据。对照组由无相应诊断的儿童组成,以便在调整年龄和性别后明确健康经济和护理相关差异。

结果

2015年,151,248名参保未成年人中有1904人(1.3%)被诊断为荨麻疹。在患荨麻疹的儿童中,70.9%至少门诊就诊过一名医生。在这些就诊中,70.9%是看儿科医生,52.5%是看全科医生,33.0%是看皮肤科医生;11%接受了住院治疗。在总共151,248名参保人员中,有1904人被诊断为荨麻疹,2015年,72.9%患荨麻疹的儿童和青少年接受了局部或全身治疗,而未患荨麻疹的为28.9%,其中患荨麻疹的儿童中有10.5%接受了局部治疗,未患荨麻疹的为2.6%,患荨麻疹的70.0%接受了全身治疗,未患荨麻疹的为27.5%接受了全身治疗。治疗荨麻疹最常用的口服药物是西替利嗪(44.2%)、泼尼松龙(9.8%)和二甲茚定(2.0%)。最常开具的局部用药是丙酸倍氯米松(49.8%)。全身用药的治疗费用为每位患者24.00欧元,而局部用药每位患者费用为1.58欧元。

结论

儿童治疗标准化指南的缺乏仍然导致各专业组之间存在模糊性和不同的治疗理念,为了实现更有效的治疗,必须消除这些问题。儿童和青少年慢性荨麻疹的治疗主要由儿科医生、全科医生和皮肤科医生进行。全身和局部用药以及住院服务是最重要的成本因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5b1/11224104/92bb4239e2e2/105_2024_5346_Fig1_HTML.jpg

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