Keller J, Andreassen T T, Joyce F, Knudsen V E, Jørgensen P H, Lucht U
Acta Orthop Scand. 1985 Aug;56(4):323-6. doi: 10.3109/17453678508993025.
Standardized osteochondral fractures in the left femoral condyle in 19 adult mongrel dogs were fixed with either fibrin sealant or Kirschner wire. Adaptation and mechanical strength after 4, 7 or 8, and 14 days were compared with an in vitro study of the initial strength of the fibrin sealant in osteochondral fractures. After 4 days, the maximum tensile strength was increased in the fibrin sealed group, whereas no difference in energy absorption at failure was found. Although the initial strength of the fibrin bond was low, the tendency to displacement was less in this group. Our results suggest that fibrin sealant can be used for fixation of small osteochondral fragments, provided that immobilisation is sufficient.
在19只成年杂种犬的左股骨髁制造标准化骨软骨骨折，分别用纤维蛋白密封剂或克氏针进行固定。通过体外研究纤维蛋白密封剂在骨软骨骨折中的初始强度，比较4天、7或8天以及14天后的适应性和机械强度。4天后，纤维蛋白密封组的最大拉伸强度增加，而在破坏时的能量吸收方面未发现差异。尽管纤维蛋白结合的初始强度较低，但该组的移位倾向较小。我们的结果表明，只要固定充分，纤维蛋白密封剂可用于固定小的骨软骨碎片。
