Gu Shuchen, Derynck Rik, Chen Ye-Guang, Feng Xin-Hua
Center for Life Sciences, Shaoxing Institute, Zhejiang University, Shaoxing, 321000, Zhejiang, China.
The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Cell Regen. 2024 May 23;13(1):11. doi: 10.1186/s13619-024-00194-x.
The family of secreted dimeric proteins known as the Transforming Growth Factor-β (TGF-β) family plays a critical role in facilitating intercellular communication within multicellular animals. A recent symposium on TGF-β Biology - Signaling, Development, and Diseases, held on December 19-21, 2023, in Hangzhou, China, showcased some latest advances in our understanding TGF-β biology and also served as an important forum for scientific collaboration and exchange of ideas. More than twenty presentations and discussions at the symposium delved into the intricate mechanisms of TGF-β superfamily signaling pathways, their roles in normal development and immunity, and the pathological conditions associated with pathway dysregulation.
被称为转化生长因子-β（TGF-β）家族的分泌型二聚体蛋白家族，在促进多细胞动物的细胞间通讯中起着关键作用。2023年12月19日至21日在中国杭州举行的最近一次关于TGF-β生物学——信号传导、发育和疾病的研讨会，展示了我们对TGF-β生物学理解的一些最新进展，同时也成为了科学合作和思想交流的重要论坛。研讨会上有二十多场报告和讨论，深入探讨了TGF-β超家族信号通路的复杂机制、它们在正常发育和免疫中的作用，以及与通路失调相关的病理状况。
