Department of Neurology, Fuyang People's Hospital, Anhui, 236000, People's Republic of China.
Department of Neurology, Fuyang Hospital Affiliated to Bengbu Medical University, Anhui, 236000, People's Republic of China.
BMC Neurol. 2024 May 23;24(1):171. doi: 10.1186/s12883-024-03678-0.
Epidemiological studies of stroke and its risk factors can help develop strategies to prevent stroke. We aimed to explore the current gender-specific prevalence of stroke and associated risk factors.
Data were collected using a structured precoded questionnaire designed by the Stroke Screening and Prevention Programme of the National Health and Wellness Commission Stroke Prevention and Control Project Committee, between June 2020 and November 2021. A total of 7394 residents took part in the study, 187 of whom had a stroke. The baseline information of each participant was obtained and included in this study. The chi-square test and Kruskal-Wallis tests were used to examine the relationship between these indicators and stroke, and then multivariate logistic regression was used to construct the prediction scale between different genders.
of 7394 participants,4571 (61.82%) were female. The overall prevalence of stroke patients in the study population was 2.53%, Multivariate analysis found that residence status (OR = 0.43, p = 0.002) 、HCY (OR = 0.962, p = 0.000)、Previous TIA (OR = 0.200, p = 0.002) 、Hypertension (OR = 0.33, p = 0.000) and Dyslipidemia (OR = 0.668, p = 0.028) were significant predictors of stroke. there are gender differences in the traditional risk factors for stroke, and women have more risk factors. ROC analysis confirmed the accuracy of the stroke risk model, and the AUC of the stroke risk model for the general population was 0.79 with p < 0.05. In the gender model, the female AUC was 0.796 (p < 0.05). and the male AUC was 0.786 with p < 0.05.
The prevalence of stroke in adults aged 40 years and above is high in eastern China were high. management of risk factors can effectively prevent the occurrence of most strokes. more attention should be paid to gender differences associated with stroke.
对卒中及其危险因素的流行病学研究有助于制定预防卒中的策略。本研究旨在探讨目前卒中的性别特异性流行情况和相关危险因素。
数据采集自国家卫生健康委脑卒中防治工程委员会卒中筛查与防治基地项目委员会设计的结构化预编码问卷，时间为 2020 年 6 月至 2021 年 11 月。共有 7394 名居民参加了研究，其中 187 人患有卒中。获得了每位参与者的基线信息，并将其纳入本研究。采用卡方检验和 Kruskal-Wallis 检验分析这些指标与卒中的关系，然后采用多变量逻辑回归构建不同性别之间的预测量表。
7394 名参与者中，4571 名（61.82%）为女性。研究人群中卒中患者的总体患病率为 2.53%。多因素分析发现，居住状况（OR=0.43，p=0.002）、HCY（OR=0.962，p=0.000）、既往 TIA（OR=0.200，p=0.002）、高血压（OR=0.33，p=0.000）和血脂异常（OR=0.668，p=0.028）是卒中的显著预测因素。卒中的传统危险因素存在性别差异，女性有更多的危险因素。ROC 分析证实了卒中风险模型的准确性，一般人群的卒中风险模型 AUC 为 0.79（p<0.05）。在性别模型中，女性的 AUC 为 0.796（p<0.05），男性的 AUC 为 0.786（p<0.05）。
中国东部 40 岁及以上成年人的卒中患病率较高。管理危险因素可有效预防大多数卒中的发生。应更加关注与卒中相关的性别差异。
