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中国卒中统计:国家神经系统疾病医疗质量监测中心、中国国家神经系统疾病临床医学研究中心、中国卒中学会、国家心血管病中心、中国疾病预防控制中心和全球神经科学与卒中协作研究所 2019 年报告更新

China Stroke Statistics: an update on the 2019 report from the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations.

机构信息

China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

National Center for Healthcare Quality Management in Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

Stroke Vasc Neurol. 2022 Oct;7(5):415-450. doi: 10.1136/svn-2021-001374. Epub 2022 Apr 20.

Abstract

China faces the greatest challenge from stroke in the world. According to results from the Global Burden of Disease Study 2019, there were 3.94 million new stroke cases, 28.76 million prevalent cases and 2.19 million deaths due to stroke in China in 2019. Furthermore, stroke is also the leading cause of disability-adjusted life-year (DALY) in China, the number of DALYs reached 45.9 million in 2019. Several recent large-scale epidemiological surveys have updated the data on pre-existing conditions contributed to stroke. The age-adjusted prevalence of overweight among Chinese adults aged 18-69 years was 34.4%, and the prevalence of obesity was 16.8% in 2018. 50.9% of Chinese adults ≥18 years of age without history of hypertension had prehypertension in 2018. The weighted prevalence of hypertension in adults was 27.5% in 2018. The weighted prevalence of total diabetes and pre-diabetes diagnosed by the American Diabetes Association criteria were 12.8% and 35.2%, respectively, among Chinese adults ≥18 years of age in 2017. The weighted atrial fibrillation prevalence was 1.8% among Chinese adults ≥45 years of age and equates to being present in an estimated 7.9 million people in China. Data from 1672 tertiary public hospitals in the Hospital Quality Monitoring System (HQMS) showed that 3 411 168 stroke cases were admitted during 2019. Of those, 2 818 875 (82.6%) were ischaemic strokes (ISs), 485 474 (14.2%) were intracerebral haemorrhages (ICHs), 106 819 (3.1%) were subarachnoid haemorrhages (SAHs). The average age was 66 years old, and 59.6% were male. A total of 1379 (<0.1%), 2604 (0.5%), 1250 (1.2%) paediatric strokes (age <18 years) were identified among IS, ICH and SAH, respectively. Over one-third (1 231 519 (36.1%)) of the stroke cases were covered by urban resident basic medical insurance, followed by urban employee basic medical insurance (891 103 (26.1%)) and new rural cooperative medical schema (543 108 (15.9%)). The leading risk factor was hypertension (57.3% for IS, 69.9% for ICH and 44.1% for SAH), and the leading comorbidity was pneumonia or pulmonary infection (10.4% for IS, 34.6% for ICH and 29.7% for SAH). In-hospital death/discharge against medical advice rate was 8.5%, ranging from 6.0% for IS to 20.6% for SAH. The median and IQR of length of stay was 9.0 (6.0-13.0) days, ranging from 10.0 (7.0-13.0) in IS to 14.0 (8.0-22.0) in ICH. Similar data from 2847 secondary public hospitals or private hospitals in the HQMS were also reported. Data from HQMS showed that higher proportions of interprovincial admission to other provinces were seen in Inner Mongolia, Anhui, Tibet and Beijing. Higher proportions of interprovincial admission from other provinces were seen in Beijng, Tianjin, Shanghai and Ningxia. Data from 323 601 strokes from 1337 hospitals in the Chinese Stroke Center Alliance during 2019 demonstrated that the composite scores of guideline-recommended key performance indicators for patients with IS, ICH and SAH were 0.78±0.20, 0.69±0.27 and 0.60±0.31, respectively.

摘要

中国面临着全球范围内最大的卒中挑战。根据 2019 年全球疾病负担研究的结果,2019 年中国有 394 万新发卒中病例、2876 万现患病例和 219 万卒中死亡病例。此外,卒中也是中国失能调整生命年 (DALY) 的主要原因,2019 年 DALY 达到 4590 万。最近几项大规模的流行病学调查更新了卒中相关既往疾病的数据。2018 年,18-69 岁中国成年人超重的年龄调整患病率为 34.4%,肥胖的患病率为 16.8%。2018 年,50.9%无高血压病史的中国成年人患有高血压前期。2018 年,成年人高血压的加权患病率为 27.5%。2017 年,中国成年人中根据美国糖尿病协会标准诊断的总糖尿病和前期糖尿病的加权患病率分别为 12.8%和 35.2%。2018 年,中国 45 岁以上成年人的加权心房颤动患病率为 1.8%,估计有 790 万人患有心房颤动。来自医院质量监测系统 (HQMS) 的 1672 家三级公立医院的数据显示,2019 年共有 3411168 例卒中患者入院。其中,2818875 例 (82.6%)为缺血性卒中 (IS),485474 例 (14.2%)为颅内出血 (ICH),106819 例 (3.1%)为蛛网膜下腔出血 (SAH)。平均年龄为 66 岁,男性占 59.6%。在 IS、ICH 和 SAH 中,分别有 1379 例 (<0.1%)、2604 例 (0.5%)和 1250 例 (1.2%)为儿童卒中。在 IS、ICH 和 SAH 中,分别有 1379 例 (<0.1%)、2604 例 (0.5%)和 1250 例 (1.2%)为儿童卒中。三分之一以上 (1231519 例,占 36.1%)的卒中病例由城镇居民基本医疗保险覆盖,其次是城镇职工基本医疗保险 (891103 例,占 26.1%)和新型农村合作医疗 (543108 例,占 15.9%)。主要危险因素是高血压 (IS 为 57.3%,ICH 为 69.9%,SAH 为 44.1%),主要合并症是肺炎或肺部感染 (IS 为 10.4%,ICH 为 34.6%,SAH 为 29.7%)。住院期间死亡率/出院时拒绝治疗率为 8.5%,范围从 IS 的 6.0%到 SAH 的 20.6%。中位和四分位间距的住院时间为 9.0 (6.0-13.0)天,范围从 IS 的 10.0 (7.0-13.0)到 ICH 的 14.0 (8.0-22.0)。HQMS 中的 2847 家二级公立医院或私立医院也报告了类似的数据。HQMS 数据显示,内蒙古、安徽、西藏和北京的跨省转诊比例较高。北京、天津、上海和宁夏的其他省份转诊比例较高。2019 年,来自中国卒中中心联盟 1337 家医院的 323601 例卒中患者的数据表明,IS、ICH 和 SAH 患者指南推荐的关键绩效指标综合评分分别为 0.78±0.20、0.69±0.27 和 0.60±0.31。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f84/9614174/69e0443fad84/svn-2021-001374f01.jpg

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