Haque Mainul, Sartelli Massimo, Haque Seraj Zohurul
Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kem Sungai Besi, 57000 Kuala Lumpur, Malaysia.
Department of Surgery, Macerata Hospital, via Santa Lucia 2, 62100 Macerata, Italy.
Dent J (Basel). 2019 Mar 1;7(1):22. doi: 10.3390/dj7010022.
Antibiotics are widely used in dental caries and another dental related issues, both for therapeutic and prophylactic reasons. Unfortunately, in recent years the use of antibiotics has been accompanied by the rapid emergence antimicrobial resistance. Dental caries and periodontal diseases are historically known as the top oral health burden in both developing and developed nations affecting around 20⁻50% of the population of this planet and the uppermost reason for tooth loss. Dental surgeons and family practitioners frequently prescribed antimicrobials for their patients as outpatient care. Several studies reported that antibiotics are often irrationally- and overprescribed in dental diseases which is the basis of antimicrobial resistance. The aim of this review is to evaluate the use of antibiotics in dental diseases. Almost certainly the promotion of primary oral health care (POHC) in primary health care program especially among the least and middle-income countries (LMIC) may be the answer to ensure and promote rational dental care.
出于治疗和预防的原因，抗生素被广泛用于龋齿及其他牙科相关问题。不幸的是，近年来抗生素的使用伴随着抗菌药物耐药性的迅速出现。龋齿和牙周疾病历来被认为是发展中国家和发达国家最主要的口腔健康负担，影响着全球约20%-50%的人口，也是牙齿脱落的最主要原因。牙科医生和家庭医生经常为患者开具抗菌药物作为门诊治疗。多项研究报告称，在牙科疾病中，抗生素常常被不合理地过度开具，这是抗菌药物耐药性产生的基础。本综述的目的是评估抗生素在牙科疾病中的使用情况。几乎可以肯定的是，在初级卫生保健项目中促进初级口腔卫生保健（POHC），尤其是在低收入和中等收入国家（LMIC），可能是确保和促进合理牙科护理的答案。
