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泰国北部上空环境空气污染物的十年趋势及其与慢性阻塞性肺疾病和肺癌的关联:2013 - 2022年

Decadal Trends in Ambient Air Pollutants and Their Association with COPD and Lung Cancer in Upper Northern Thailand: 2013-2022.

作者信息

Sapbamrer Pachara, Assavanopakun Pheerasak, Panumasvivat Jinjuta

机构信息

Department of Academic, Montfort College, Chiang Mai 50000, Thailand.

Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

出版信息

Toxics. 2024 Apr 28;12(5):321. doi: 10.3390/toxics12050321.

Abstract

Air pollution in upper northern Thailand raises health concerns. This study examined trends and associations between air pollutants and respiratory diseases, focusing on COPD and lung cancer during haze (December-May) and non-haze (June-November) seasons in upper northern Thailand from 2013 to 2022. This study utilized data from the Pollution Control Department and Chiang Mai Provincial Public Health. The key air pollutants included PM, PM, SO, NO, CO, and O. Respiratory disease data included fatality rates for lung cancer and COPD and the re-admission rate for COPD. Results indicated peak air pollutant levels and COPD re-admission rates in March, with PM concentrations exceeding air quality standards from January to April. During haze periods, COPD fatality and re-admission rates significantly increased (mean difference: 0.43 and 4.23 per 1000-case population, respectively; < 0.001), while lung cancer fatality rates were higher without statistical significance. Pearson correlation analysis found positive correlations between PM, PM, O, and NO concentrations and COPD re-admission and fatality rates at 0-1 month lag times, with a declining trend observed at subsequent lag intervals of 2 to 3 months. Overall, this study highlights the predictable pattern of air pollution in the region, correlating with higher COPD fatality and re-admission rates.

摘要

泰国北部上空的空气污染引发了人们对健康的担忧。本研究调查了空气污染物与呼吸道疾病之间的趋势和关联,重点关注2013年至2022年泰国北部上空雾霾季(12月至次年5月)和非雾霾季(6月至11月)期间的慢性阻塞性肺疾病(COPD)和肺癌情况。本研究使用了来自污染控制部门和清迈省公共卫生部门的数据。主要空气污染物包括颗粒物(PM)、二氧化硫(SO)、氮氧化物(NO)、一氧化碳(CO)和臭氧(O)。呼吸道疾病数据包括肺癌和慢性阻塞性肺疾病的死亡率以及慢性阻塞性肺疾病的再入院率。结果表明,3月空气污染物水平和慢性阻塞性肺疾病再入院率达到峰值,1月至4月期间颗粒物浓度超过空气质量标准。在雾霾期间,慢性阻塞性肺疾病的死亡率和再入院率显著上升(平均差异分别为每1000例病例0.43和4.23;<0.001),而肺癌死亡率较高,但无统计学意义。Pearson相关性分析发现,在滞后0至1个月时,颗粒物、臭氧和氮氧化物浓度与慢性阻塞性肺疾病的再入院率和死亡率之间存在正相关,在随后2至3个月的滞后间隔中呈下降趋势。总体而言,本研究突出了该地区空气污染的可预测模式,这与慢性阻塞性肺疾病较高的死亡率和再入院率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd5/11125922/072a98116614/toxics-12-00321-g001.jpg

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