Mollnes T E
Complement. 1985;2(2-3):156-64. doi: 10.1159/000467856.
Activation of the initial part (early phase) and terminal part (late phase) of the complement cascade was examined. C3d,g and the fluid-phase terminal complement complex were quantified and compared after spontaneous in vitro activation and after acute in vivo activation caused by extracorporeal circulation during coronary artery surgery. The results suggest that there is a close but not complete correlation between early- and late-phase activation of complement, that C3d,g and the terminal complement complex have different elimination rates in vivo, and that these two indicators are valuable for evaluation of early- and late-phase activation, respectively.
对补体级联反应初始部分（早期阶段）和终末部分（晚期阶段）的激活情况进行了检测。在体外自发激活以及冠状动脉手术期间体外循环导致的急性体内激活后，对C3d,g和液相终末补体复合物进行了定量和比较。结果表明，补体早期和晚期激活之间存在密切但不完全的相关性，C3d,g和终末补体复合物在体内具有不同的清除率，并且这两个指标分别对评估早期和晚期激活具有价值。
