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药用植物中的生物活性化合物作为治疗轻度寻常痤疮的潜在佐剂。

Bioactive Compounds from Medicinal Plants as Potential Adjuvants in the Treatment of Mild Acne Vulgaris.

机构信息

Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.

出版信息

Molecules. 2024 May 19;29(10):2394. doi: 10.3390/molecules29102394.

Abstract

In recent years, there has been a growing interest in the use of medicinal plants and phytochemicals as potential treatments for acne vulgaris. This condition, characterized by chronic inflammation, predominantly affects adolescents and young adults. Conventional treatment typically targets the key factors contributing to its development: the proliferation of and the associated inflammation. However, these treatments often involve the use of potent drugs. As a result, the exploration of herbal medicine as a complementary approach has emerged as a promising strategy. By harnessing the therapeutic properties of medicinal plants and phytochemicals, it may be possible to address acne vulgaris while minimizing the reliance on strong drugs. This approach not only offers potential benefits for individuals seeking alternative treatments but also underscores the importance of natural remedies of plant origin in dermatological care. The primary aim of this study was to assess the antimicrobial, antioxidant, and anti-inflammatory properties of plants and their phytochemical constituents in the management of mild acne vulgaris. A comprehensive search of scientific databases was conducted from 2018 to September 2023. The findings of this review suggest that medicinal plants and their phytochemical components hold promise as treatments for mild acne vulgaris. However, it is crucial to note that further research employing high-quality evidence and standardized methodologies is essential to substantiate their efficacy and safety profiles.

摘要

近年来,人们对药用植物和植物化学物质作为治疗寻常痤疮的潜在方法越来越感兴趣。这种以慢性炎症为特征的疾病主要影响青少年和年轻人。常规治疗通常针对导致其发展的关键因素:和相关炎症的增殖。然而,这些治疗通常涉及使用强效药物。因此,探索草药作为一种补充方法已成为一种有前途的策略。通过利用药用植物和植物化学物质的治疗特性,可能在最小化对强药物依赖的同时,解决寻常痤疮问题。这种方法不仅为寻求替代治疗的个体提供了潜在的益处,还强调了植物来源的天然疗法在皮肤科护理中的重要性。本研究的主要目的是评估植物及其植物化学成分在管理轻度寻常痤疮中的抗菌、抗氧化和抗炎特性。从 2018 年到 2023 年 9 月,对科学数据库进行了全面检索。该综述的结果表明,药用植物及其植物化学成分可能是治疗轻度寻常痤疮的有效方法。然而,必须注意的是,需要进一步采用高质量证据和标准化方法进行研究,以证实其疗效和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82ee/11124055/7736316249f2/molecules-29-02394-g001.jpg

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