Mental Health Data Science Division, New York State Psychiatric Institute, New York, NY, United States of America; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, United States of America.
Mental Health Data Science Division, New York State Psychiatric Institute, New York, NY, United States of America; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, United States of America; Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.
J Affect Disord. 2024 Sep 1;360:268-275. doi: 10.1016/j.jad.2024.05.093. Epub 2024 May 23.
Ecological Momentary Assessment (EMA) holds promise for providing insights into daily life experiences when studying mental health phenomena. However, commonly used mixed-effects linear statistical models do not fully utilize the richness of the ultidimensional time-varying data that EMA yields. Recurrent Neural Networks (RNNs) provide an alternative data analytic method to leverage more information and potentially improve prediction, particularly for non-normally distributed outcomes.
As part of a broader research study of suicidal thoughts and behavior in people with borderline personality disorder (BPD), eighty-four participants engaged in EMA data collection over one week, answering questions multiple times each day about suicidal ideation (SI), stressful events, coping strategy use, and affect. RNNs and mixed-effects linear regression models (MEMs) were trained and used to predict SI. Root mean squared error (RMSE), mean absolute percent error (MAPE), and a pseudo-R accuracy metric were used to compare SI prediction accuracy between the two modeling methods.
RNNs had superior accuracy metrics (full model: RMSE = 3.41, MAPE = 42 %, pseudo-R = 26 %) compared with MEMs (full model: RMSE = 3.84, MAPE = 56 %, pseudo-R = 16 %). Importantly, RNNs showed significantly more accurate prediction at higher values of SI. Additionally, RNNs predicted, with significantly higher accuracy, the SI scores of participants with depression diagnoses and of participants with higher depression scores at baseline.
In this EMA study with a moderately sized sample, RNNs were better able to learn and predict daily SI compared with mixed-effects models. RNNs should be considered as an option for EMA analysis.
生态瞬时评估(EMA)有望为研究心理健康现象时提供对日常生活体验的深入了解。然而,常用的混合效应线性统计模型并没有充分利用 EMA 产生的多维时变数据的丰富性。递归神经网络(RNN)提供了一种替代数据分析方法,可以利用更多信息并有可能提高预测能力,特别是对于非正态分布的结果。
作为一项关于边缘型人格障碍(BPD)患者自杀思维和行为的更广泛研究的一部分,84 名参与者在一周内进行了 EMA 数据收集,每天多次回答关于自杀意念(SI)、压力事件、应对策略使用和情绪的问题。RNN 和混合效应线性回归模型(MEM)被训练并用于预测 SI。均方根误差(RMSE)、平均绝对百分比误差(MAPE)和伪 R 准确性指标用于比较两种建模方法的 SI 预测准确性。
RNN 的准确性指标(完整模型:RMSE=3.41,MAPE=42%,伪 R=26%)优于 MEM(完整模型:RMSE=3.84,MAPE=56%,伪 R=16%)。重要的是,RNN 在 SI 值较高的情况下表现出更准确的预测。此外,RNN 以更高的准确性预测了具有抑郁诊断的参与者和基线时抑郁得分较高的参与者的 SI 得分。
在这项具有中等规模样本的 EMA 研究中,RNN 比混合效应模型更能学习和预测日常 SI。RNN 应被视为 EMA 分析的一种选择。