Carrasco Rojas Yanet Isabel, Turpo Peqqueña Albert Gabriel, Zenteno Tejada Natalia Camila, Quispe Pastor Victoria Elena, Martínez San Martín Juan Augusto, Chambilla Huellcacure Evelyn Maria
Surgical Oncology Service, Carlos Alberto Seguín Escobedo National Hospital (HNCASE), EsSalud, Peral - El Filtro, S/N, Arequipa 04001, Peru.
Faculty of Human Medicine, Center for Research and Medical Studies (CIEM), Catholic University of Santa María, Urb San José s/n, Umacollo, Arequipa 04013, Peru.
Ecancermedicalscience. 2025 May 27;19:1910. doi: 10.3332/ecancer.2025.1910. eCollection 2025.
Gastric schwannomas (GS) are rare tumours originating from Schwann cells that affect the gastrointestinal tract, posing a diagnostic challenge due to their nonspecific symptoms. We report the case of a 61-year-old female presented with gastric fullness and occasional episodes of abdominal pain. Computed tomography revealed a solid mass in the lesser curvature of the stomach, initially suspected to be a gastrointestinal stromal tumours. During surgery, an exophytic lesion was identified and confirmed histopathologically and immunohistochemically as a gastric schwannoma. GS should be considered in the differential diagnosis of gastric subepithelial tumours. Its diagnosis relies on immunohistochemistry, and surgical resection ensures effective treatment.
胃神经鞘瘤（GS）是起源于施万细胞的罕见肿瘤，可累及胃肠道，因其症状不具特异性，故诊断颇具挑战。我们报告一例61岁女性病例，该患者表现为胃部饱胀及偶尔发作的腹痛。计算机断层扫描显示胃小弯处有一实性肿块，最初怀疑为胃肠道间质瘤。手术过程中发现一个外生性病变，经组织病理学和免疫组织化学检查确诊为胃神经鞘瘤。在胃上皮下肿瘤的鉴别诊断中应考虑胃神经鞘瘤。其诊断依赖免疫组织化学，手术切除可确保有效治疗。
