Department of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
J Vet Intern Med. 2024 Jul-Aug;38(4):2151-2157. doi: 10.1111/jvim.17119. Epub 2024 May 27.
Hemotropic mycoplasmas, hemoplasmas, are epi-erythrocytic parasitic bacteria that can be transmitted through blood transfusion.
To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between Hemoplasma spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables.
Seven thousand five hundred seventy-three blood units from 4121 privately-owned potential donor cats.
Retrospective observational cross-sectional study. The Banco Sangue Animal (BSA)-Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood-borne pathogens screening tests were extracted from the medical records.
Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for Hemoplasma spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%-5.9%) in potential blood donors. Using multivariable generalized estimation equation models, Hemoplasma spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4-2.6, P < .0001), units positive for FeLV (OR = 2.8, 95% CI: 1.4-5.6, P = .0023), and units collected in winter months (OR = 2.5, 95% CI: 1.7-3.6, P < .0001).
This study underscores the importance of Hemoplasma spp. and other relevant blood-borne pathogens screening at every donation. Implementing stringent screening protocols is crucial to mitigate the risk of hemoplasma transmission via blood transfusions, thereby safeguarding the health and welfare of cats receiving transfusions.
血源支原体（hemotropic mycoplasmas），也称为血原体，是一种寄生在红细胞表面的细菌，可以通过输血传播。
研究潜在的猫科动物献血者的血原体感染流行率，并调查血液单位中血原体 spp. 的定量聚合酶链反应（qPCR）阳性与选定变量之间的关联。
来自 4121 只私人拥有的潜在供体猫的 7573 个血液单位。
回顾性观察性横断面研究。回顾了 2022 年在葡萄牙、西班牙和比利时进行的所有猫科动物献血的 Banco Sangue Animal（BSA）-动物血库医疗数据库。从病历中提取了基本特征和血液传播病原体筛查试验的结果。
2022 年，在 4034 只葡萄牙供体猫中有 212 只和 70 只西班牙供体猫的血原体 spp. qPCR 检测呈阳性，导致潜在献血者的总体估计患病率为 5.2%（95%CI：4.5%-5.9%）。使用多变量广义估计方程模型，血原体 spp. qPCR 在雄性猫（OR=1.9，95%CI：1.4-2.6，P<0.0001）、FeLV 阳性（OR=2.8，95%CI：1.4-5.6，P=0.0023）和冬季月份采集的血液单位（OR=2.5，95%CI：1.7-3.6，P<0.0001）中更为常见。
本研究强调了在每次献血时都要进行血原体 spp. 和其他相关血液传播病原体筛查的重要性。实施严格的筛查方案对于降低通过输血传播血原体的风险至关重要，从而保障接受输血的猫的健康和福利。
