普通牙膏抗牙菌斑剂对[具体微生物名称1]和[具体微生物名称2]的抗菌效果：一项体外研究。 （注：原文中“and”后面缺少具体内容，这里补充了[具体微生物名称1]和[具体微生物名称2]以便完整理解句子结构）
Antimicrobial efficacy of antiplaque agents of common toothpastes against and : An study.
作者信息
Naghsh Narges, Yaghini Jaber, Narimani Tahmineh, Khodarahmi Elahe
机构信息
Department of Peridontics, Dental Implants Research Center Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Dent Res J (Isfahan). 2024 Mar 26;21:20. eCollection 2024.
BACKGROUND
This study was designed to evaluate the antimicrobial activity of common gum protection and antiplaque toothpastes against () and () as important periodontal pathogens.
MATERIALS AND METHODS
This experimental study investigated the antimicrobial activity of 15 commonly used toothpastes from different companies on the two common types of periopathogens, and . The antimicrobial activity of toothpaste was evaluated at three concentrations of 100%, 50%, and 25% and analyzed by agar well diffusion plate method and zone of inhibition. The obtained data were compared and statistically analyzed by SPSS software using one-way ANOVA and the least significant difference tests (α = 0.05).
RESULTS
One-way ANOVA showed that the mean diameter of the two-bacterial zone of inhibition was significantly different at 100%, 50%, and 25% concentrations of toothpastes ( < 0.001). In general, the mean diameter of the zone of inhibition was greater at 100% concentration than the other two concentrations in all toothpastes. The highest zone of inhibition of the was in the toothpastes containing tin. Further, the highest zone of inhibition of was found in the triclosan-containing toothpastes.
CONCLUSION
Toothpastes containing triclosan had the most antimicrobial activity against . Moreover, toothpastes containing tin compounds had the most antimicrobial effect against .
背景
本研究旨在评估常见的护龈和抗牙菌斑牙膏对作为重要牙周病原体的（）和（）的抗菌活性。
材料与方法
本实验研究调查了来自不同公司的15种常用牙膏对两种常见牙周病原体和的抗菌活性。牙膏的抗菌活性在100%、50%和25%三种浓度下进行评估，并通过琼脂孔扩散平板法和抑菌圈进行分析。所得数据使用SPSS软件进行比较，并通过单因素方差分析和最小显著差异检验（α = 0.05）进行统计分析。
结果
单因素方差分析表明，在牙膏浓度为100%、50%和25%时，两种细菌的抑菌圈平均直径存在显著差异（< 0.001）。总体而言，在所有牙膏中，100%浓度下的抑菌圈平均直径大于其他两种浓度。的最高抑菌圈出现在含锡的牙膏中。此外，的最高抑菌圈出现在含三氯生的牙膏中。
结论
含三氯生的牙膏对具有最强的抗菌活性。此外，含锡化合物的牙膏对具有最强的抗菌作用。
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