Mehta J, Mehta P
Am Heart J. 1985 Jan;109(1):1-3. doi: 10.1016/0002-8703(85)90407-7.
We examined the generation of prostacyclin and thromboxane A2 in the right atrial tissues obtained from patients undergoing coronary bypass surgery. In all instances, the capability of atrial tissues to produce these potent prostaglandins was identified. The identity of prostacyclin and thromboxane A2 was confirmed by use of specific radioimmunoassays of stable metabolites and by use of specific thromboxane A2 synthetase and cyclo-oxygenase inhibitors.
我们检测了接受冠状动脉搭桥手术患者右心房组织中前列环素和血栓素A2的生成情况。在所有病例中，均发现心房组织具有产生这些强效前列腺素的能力。通过对稳定代谢产物进行特异性放射免疫测定以及使用特异性血栓素A2合成酶和环氧化酶抑制剂，证实了前列环素和血栓素A2的特性。
