Pisabarro A G, de Pedro M A, Vázquez D
J Bacteriol. 1985 Jan;161(1):238-42. doi: 10.1128/jb.161.1.238-242.1985.
By determining the composition in muropeptides of the murein of a number of strains of Escherichia coli, purified from cells at various states of growth, the sacculus was found to be considerably modified when cells stop active growth. Murein from resting cells becomes hypercross-linked and richer in covalently bound lipoprotein, whereas the mean length of the glycan chains is considerably reduced. The alteration of the sacculus occurs progressively during the transitions from active growth to stationary phase and vice versa.
通过测定从处于不同生长状态的细胞中纯化得到的多种大肠杆菌菌株细胞壁肽聚糖的肽聚糖组成,发现当细胞停止活跃生长时,细胞壁会发生显著改变。静止细胞的肽聚糖会过度交联,共价结合脂蛋白的含量增加,而聚糖链的平均长度则显著缩短。在从活跃生长到稳定期的转变过程中,以及反之亦然的过程中,细胞壁的改变是逐渐发生的。