Department of Physical Activities and Health Sciences, Faculty of Sports Studies, Masaryk University, Brno, Czech Republic.
Department of Physical Education and Social Sciences, Faculty of Sports Studies, Masaryk University, Brno, Czech Republic.
PLoS One. 2024 May 31;19(5):e0303925. doi: 10.1371/journal.pone.0303925. eCollection 2024.
The study investigated the association between knee joint muscle strength and the prevalence of depression in a cohort of young adults.
The observational, population-based study was performed with 909 participants (29.02 ± 2.03 years; 48.73% male) from the Central European Longitudinal Studies of Parents and Children: Young Adults (CELSPAC: YA), who were retained to analysis. Quadriceps and hamstring knee muscle strength were assessed by isokinetic dynamometry, and depression by Beck's Depression Inventory (BDI-II). Statistical comparisons (Mann-Whitney and Chi-squared test) and effect size analyses (Eta-Squared, and Odds Ratio) were conducted.
The main findings revealed an inverse association between knee joint muscle strength and depression, with individuals who had low muscle strength having 3.15 (95% CI = 2.74-3.62) times higher odds of experiencing depression. Specifically, participants with low extensor strength had 4.63 (95% CI = 2.20-9.74) times higher odds, and those with low flexor strength had 2.68 (95% CI = 1.47-4.89) times higher odds of experiencing depression compared to those individuals with high muscle strength. Furthermore, gender-specific analyses revealed that males with low muscle strength had 2.51 (95% CI = 1.53-4.14) times higher odds, while females had 3.46 (95% CI = 2.93-4.08) times higher odds of experiencing depression compared to individuals with high muscle strength.
Strong knee muscles seems to be a key factor in preventing depression, specially in female young adults. The results support the importance of promoting an increase in muscle strength through physical activity as a preventive strategy against depression in this population.
本研究旨在探讨膝关节肌肉力量与年轻成年人抑郁患病率之间的关系。
这是一项观察性、基于人群的研究，共纳入了来自中欧父母与子女纵向研究：年轻人（CELSPAC：YA）的 909 名参与者（29.02±2.03 岁，48.73%为男性），并对其进行了分析。通过等速测力仪评估股四头肌和腘绳肌的膝关节肌肉力量，采用贝克抑郁自评量表（BDI-II）评估抑郁情况。进行了统计学比较（Mann-Whitney 和卡方检验）和效应量分析（Eta-平方和优势比）。
主要发现表明膝关节肌肉力量与抑郁之间存在负相关，肌肉力量较弱的个体患抑郁的风险高 3.15 倍（95%CI=2.74-3.62）。具体而言，伸肌力量较弱的参与者患抑郁的风险高 4.63 倍（95%CI=2.20-9.74），屈肌力量较弱的参与者患抑郁的风险高 2.68 倍（95%CI=1.47-4.89），与肌肉力量较强的参与者相比。此外，性别特异性分析显示，男性肌肉力量较弱的个体患抑郁的风险高 2.51 倍（95%CI=1.53-4.14），而女性肌肉力量较弱的个体患抑郁的风险高 3.46 倍（95%CI=2.93-4.08），与肌肉力量较强的个体相比。
强壮的膝关节肌肉似乎是预防抑郁的关键因素，特别是对年轻女性。研究结果支持通过体育活动增加肌肉力量作为预防该人群抑郁的重要策略。
