Nuffield Department of Population Health, University of Oxford, Oxford, UK
Nuffield Department of Population Health, University of Oxford, Oxford, UK.
J Epidemiol Community Health. 2024 Jul 10;78(8):500-507. doi: 10.1136/jech-2024-222060.
In the United Kingdom, pregnant women who live in the most deprived areas have two times the risk of dying than those who live in the least deprived areas. There are even greater disparities between women from different ethnic groups. The aim of this study was to investigate the role of area-based deprivation and ethnicity in the increased risk of severe maternal morbidity (SMM), in primiparous women in England.
A retrospective nationwide population study was conducted using English National Hospital Episode Statistics Admitted Patient Care database. All primiparous women were included if they gave birth in an National Healthcare Service (NHS) hospital in England between 1 January 2016 and 31 December 2021. Logistic regression was used to examine the relative odds of SMM by Index of Multiple Deprivation and ethnicity, adjusting for age and health behaviours, medical and psychological factors.
The study population comprised 1 178 756 primiparous women. Neighbourhood deprivation increased the risk of SMM at the time of childbirth. In the fully adjusted model, there was a linear trend (p=0.001) between deprivation quintile and the odds of SMM. Being from a minoritised ethnic group also independently increased the risk of SMM, with black or black British African women having the highest risk, adjusted OR 1.84 (95% CI 1.70 to 2.00) compared with white women. There was no interaction between deprivation and ethnicity (p=0.49).
This study has highlighted that neighbourhood deprivation and ethnicity are important, independently associated risk factors for SMM.
在英国,生活在最贫困地区的孕妇死亡风险是生活在最不贫困地区的孕妇的两倍。不同族裔的女性之间存在更大的差异。本研究旨在调查地区贫困程度和族裔在英格兰初产妇严重产妇发病率(SMM)风险增加中的作用。
本研究采用回顾性全国人群研究方法,使用英国国家医院发病统计入院患者护理数据库。如果初产妇在 2016 年 1 月 1 日至 2021 年 12 月 31 日期间在英格兰的国民保健服务(NHS)医院分娩,则将其纳入研究。使用逻辑回归检查社会经济剥夺指数和族裔与 SMM 的相对比值,调整年龄和健康行为、医疗和心理因素。
本研究人群包括 1178756 名初产妇。社区贫困程度增加了分娩时 SMM 的风险。在完全调整的模型中,社会经济剥夺五分位数与 SMM 的比值呈线性趋势(p=0.001)。属于少数民族群体也会增加 SMM 的风险,与白人妇女相比,黑人或黑人英裔非洲妇女的风险最高,调整后的比值比为 1.84(95%CI 1.70 至 2.00)。社会经济剥夺和族裔之间没有交互作用(p=0.49)。
本研究强调了社区贫困程度和族裔是 SMM 的重要、独立的相关危险因素。