Laggner A, Kleinberger G, Sommer G, Haller J, Lenz K, Base W, Druml W
Schweiz Med Wochenschr. 1985 Feb 9;115(6):210-3.
Measurement of extravascular lung water (EVLW) was performed by the thermal-dye technique in 55 critically ill patients. The EVLW values were compared with the corresponding radiographic, hemodynamic and functional pulmonary data. EVLW values revealed a positive correlation with the chest X-ray score (CXR) (r = 0.836; p less than 0.001), mean pulmonary artery pressure (PP) (r = 0.414; p less than 0.01), pulmonary capillary wedge pressure (PCWP) (r = 0.353; p less than 0.01), venous admixture (Qs/Qt) (r = 0.288; p less than 0.05), and alveo-arterial oxygen difference/fraction of inspired oxygen (AaDO2/FiO2) (r = 0.441; p less than 0.001). No correlation was found between EVLW values and colloid-osmotic pressure minus PCWP (COP-PCWP) (r = 0.221). Though different positive correlations between EVLW values and these parameters were found, they cannot replace EVLW measurement. Rather, EVLW measurement provides additional information on the degree of pulmonary edema which is useful in differentiating between cardiac and non-cardiac pulmonary edema and in states of radiologic over- or underestimation of EVLW.
采用热染料技术对55例危重症患者进行血管外肺水(EVLW)测量。将EVLW值与相应的影像学、血流动力学及肺功能数据进行比较。EVLW值与胸部X线评分(CXR)呈正相关(r = 0.836;p < 0.001),与平均肺动脉压(PP)呈正相关(r = 0.414;p < 0.01),与肺毛细血管楔压(PCWP)呈正相关(r = 0.353;p < 0.01),与静脉血掺杂(Qs/Qt)呈正相关(r = 0.288;p < 0.05),与肺泡 - 动脉氧分压差/吸入氧分数(AaDO2/FiO2)呈正相关(r = 0.441;p < 0.001)。未发现EVLW值与胶体渗透压减去PCWP(COP - PCWP)之间存在相关性(r = 0.221)。尽管发现EVLW值与这些参数之间存在不同的正相关关系,但它们不能替代EVLW测量。相反,EVLW测量可提供有关肺水肿程度的额外信息,这对于区分心源性和非心源性肺水肿以及在EVLW影像学高估或低估的情况下很有用。