Institut de Recerca Sant Joan de Déu, Parc Sanitari Sant Joan de Déu, Esplugues de Llobregat, Sant Boi de Llobregat. CIBERSAM, Spain.
Mental Health Department, Hospital Regional Universitario de Málaga, University of Malaga, Malaga, Spain.
Arch Womens Ment Health. 2024 Oct;27(5):721-729. doi: 10.1007/s00737-024-01472-y. Epub 2024 Jun 5.
to study sex differences in self-reported symptoms measured with the Scale of Patient-Reported Impact of Symptoms in Schizophrenia (PRISS), to investigated sex differences in the degree of agreements between self-reported symptoms and clinical symptoms assessed by professionals, and to identify which clinical and sociodemographic variables predicted a greater presence of self-reported symptoms split by sex.
161 patients (37 females; 124 males), aged between 18 and 65 years, with a diagnosis of schizophrenia assisted in non-acute mental health services at four mental health catchment areas in Andalucia and Catalonia were included. The PRISS scale was administered to asses self-reported symptoms.
males reported higher presence of excitement, grandiosity, motor retardation and poor attention) than women. There was less agreement in the presence of psychotic symptoms in men than in women when comparing self-reported symptoms and clinical symptoms assessed by professionals. Finally, in men the predictors variables for the greater presence of self-perceived symptoms were greater psychotic symptomatology and more disability, while in women were greater presence of alogia and higher doses of chlorpromazine.
Assessing and being aware of the self-perceived symptoms of patients with schizophrenia should be considered in the clinic, especially in men, as there appears to be a lack of agreement on certain items. This would allow treatments to be more focused on patients' need by sex, and would make them feel part of the therapeutic process, improving their therapeutic adherence, evolution and quality of life.
研究使用精神分裂症患者报告影响量表（PRISS）评估的自我报告症状中的性别差异，调查自我报告症状与专业人员评估的临床症状之间的一致性程度中的性别差异，并确定哪些临床和社会人口统计学变量可预测按性别划分的自我报告症状的更大存在。
纳入了 161 名年龄在 18 至 65 岁之间、被诊断为精神分裂症的患者（37 名女性；124 名男性），他们在安达卢西亚和加泰罗尼亚的四个精神卫生服务区的非急性精神卫生服务中接受治疗。使用 PRISS 量表评估自我报告症状。
男性报告的兴奋、夸大、运动迟缓和注意力不集中等症状比女性更为常见。与专业人员评估的自我报告症状和临床症状相比，男性出现的精神病症状一致性较低。最后，在男性中，预测自我感知症状更大存在的变量是更严重的精神病症状和更多的残疾，而在女性中，预测变量是更严重的思维贫乏和更高剂量的氯丙嗪。
在临床中应考虑评估和意识到精神分裂症患者的自我感知症状，特别是在男性中，因为在某些项目上似乎存在不一致。这将使治疗更加关注患者的性别需求，并使他们感到自己是治疗过程的一部分，从而提高他们的治疗依从性、病情进展和生活质量。
