Rolls Edmund T, Feng Jianfeng, Zhang Ruohan
Department of Computer Science, University of Warwick, Coventry, CV4 7AL, UK.
Institute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai, 200403, China.
Brain Struct Funct. 2024 Jul;229(6):1471-1493. doi: 10.1007/s00429-024-02811-6. Epub 2024 Jun 5.
Connectivity maps are now available for the 360 cortical regions in the Human Connectome Project Multimodal Parcellation atlas. Here we add function to these maps by measuring selective fMRI activations and functional connectivity increases to stationary visual stimuli of faces, scenes, body parts and tools from 956 HCP participants. Faces activate regions in the ventrolateral visual cortical stream (FFC), in the superior temporal sulcus (STS) visual stream for face and head motion; and inferior parietal visual (PGi) and somatosensory (PF) regions. Scenes activate ventromedial visual stream VMV and PHA regions in the parahippocampal scene area; medial (7m) and lateral parietal (PGp) regions; and the reward-related medial orbitofrontal cortex. Body parts activate the inferior temporal cortex object regions (TE1p, TE2p); but also visual motion regions (MT, MST, FST); and the inferior parietal visual (PGi, PGs) and somatosensory (PF) regions; and the unpleasant-related lateral orbitofrontal cortex. Tools activate an intermediate ventral stream area (VMV3, VVC, PHA3); visual motion regions (FST); somatosensory (1, 2); and auditory (A4, A5) cortical regions. The findings add function to cortical connectivity maps; and show how stationary visual stimuli activate other cortical regions related to their associations, including visual motion, somatosensory, auditory, semantic, and orbitofrontal cortex value-related, regions.
人类连接组计划多模态脑图谱中的360个皮质区域现在已有连接图谱。在此，我们通过测量956名人类连接组计划参与者对人脸、场景、身体部位和工具的静态视觉刺激的选择性功能磁共振成像激活和功能连接增加情况，为这些图谱增添了功能。人脸激活腹外侧视觉皮质流（FFC）中的区域、颞上沟（STS）视觉流中用于人脸和头部运动的区域，以及顶下视觉（PGi）和体感（PF）区域。场景激活腹内侧视觉流VMV和海马旁场景区域中的PHA区域；内侧（7m）和外侧顶叶（PGp）区域；以及与奖赏相关的内侧眶额皮质。身体部位激活颞下皮质物体区域（TE1p、TE2p）；但也激活视觉运动区域（MT、MST、FST）；以及顶下视觉（PGi、PGs）和体感（PF）区域；以及与不愉快相关的外侧眶额皮质。工具激活中间腹侧流区域（VMV3、VVC、PHA3）；视觉运动区域（FST）；体感（1、2）；以及听觉（A4、A5）皮质区域。这些发现为皮质连接图谱增添了功能；并展示了静态视觉刺激如何激活与其关联相关的其他皮质区域，包括视觉运动、体感、听觉、语义以及与眶额皮质价值相关的区域。
