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揭示治疗可能性:对咖啡酸的全面探索

Revealing the Curative Possibilities: A Comprehensive Exploration of Caffeic Acid.

作者信息

Goyal Ahsas, Singh Vishwa Deep, Solanki Kunal, Verma Aanchal

机构信息

Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.

出版信息

Curr Pharm Biotechnol. 2024 Jun 4. doi: 10.2174/0113892010309341240517071344.

Abstract

Caffeic acid, a phenolic compound of the hydroxycinnamic acid family, is abundant in various plant-based foods, such as fruits, vegetables, and coffee, alongside other biologically active compounds. Recognizing its potential to address various health issues and its widespread presence in commonly consumed foods underscores the importance of comprehending and harnessing the benefits of caffeic acid for human nutrition and well-being. This versatile substance, characterized by acrylic and phenolic functional groups, plays a pivotal role in the food and pharmaceutical industries. Furthermore, a detailed exploration of its pharmacokinetic properties, absorption, distribution, metabolism, and excretion enhances our understanding of how the human body processes it. Functioning as a precursor for essential compounds, caffeic acid contributes to formulations with notable anti-inflammatory, antiviral, anti-cancer, anti-diabetic, antibacterial, neuroprotective, and hepatoprotective qualities. Its current applications in treating Parkinson's and Alzheimer's disease underscore its therapeutic significance. This comprehensive analysis sheds light on caffeic acid's importance, showcasing its diverse applications across various domains and paving the way for further research and development to fully unlock its therapeutic potential. In conclusion, caffeic acid emerges as a bioactive substance with a broad spectrum of pharmacological properties, suggesting its potential utility in diverse therapeutic contexts. The comprehensive information provided in this article serves as a foundation for further research and learning regarding the various ways that caffeic acid supports human health.

摘要

咖啡酸是羟基肉桂酸家族的一种酚类化合物,与其他生物活性化合物一起,大量存在于各种植物性食物中,如水果、蔬菜和咖啡。认识到其解决各种健康问题的潜力以及在常见食用食物中的广泛存在,凸显了理解和利用咖啡酸对人类营养与健康益处的重要性。这种具有丙烯酸和酚类官能团的多功能物质,在食品和制药行业中发挥着关键作用。此外,对其药代动力学性质、吸收、分布、代谢和排泄的详细探索,增进了我们对人体如何处理它的理解。作为必需化合物的前体,咖啡酸有助于制备具有显著抗炎、抗病毒、抗癌、抗糖尿病、抗菌、神经保护和肝脏保护特性的制剂。其目前在治疗帕金森病和阿尔茨海默病方面的应用凸显了其治疗意义。这一全面分析揭示了咖啡酸的重要性,展示了其在各个领域的多样应用,并为进一步研究和开发以充分释放其治疗潜力铺平了道路。总之,咖啡酸是一种具有广泛药理特性的生物活性物质,表明其在多种治疗环境中的潜在效用。本文提供的全面信息为进一步研究和了解咖啡酸支持人类健康的各种方式奠定了基础。

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