Andrade Mena C E, Orbach-Arbouys S, Mathé G
Int Arch Allergy Appl Immunol. 1985;76(4):341-3. doi: 10.1159/000233718.
Following the intraperitoneal injection of cis-diamino-dichloro-platinum (II) (CDDP) into tumor-bearing mice, two immune responses were augmented. The total splenic plaque-forming cells response to sheep red blood cells and the delayed-type hypersensitivity reaction to oxazolone were higher in treated animals than in the control groups. This observation may be relevant in the establishment of clinical protocols associating CDDP and other cytotoxic drugs.
给荷瘤小鼠腹腔注射顺二氨基二氯铂（II）（CDDP）后，两种免疫反应增强。与对照组相比，经处理的动物对绵羊红细胞的脾集落形成细胞总数反应以及对恶唑酮的迟发型超敏反应更高。这一观察结果可能与制定联合使用CDDP和其他细胞毒性药物的临床方案相关。
