使用组胺风团试验检测局部美白制剂中的类固醇。

Nithya Satish, Srinivas Chakravarthi R, Lal Surendranath

Department of Dermatology, Ranga's Centre of Dermatology, Coimbatore, Tamil Nadu, India.

Department of Dermatology, Venereology and Leprology, Kalinga Institute of Medical Sciences (KIMS), KIIT University, Bhubaneswar, Odisha, India.

Indian Dermatol Online J. 2024 Feb 13;15(3):504-506. doi: 10.4103/idoj.idoj_321_23. eCollection 2024 May-Jun.

Topical corticosteroid (TC) abuse is a common, worldwide, problem. One of the recent emerging concerns is the adulteration of TC in fairness cream. The presence of TC in skin-whitening cosmetic creams can be detected by high-performance liquid chromatography (HPLC). Since HPLC is expensive, time-taking and not easily available, we suggest the use of histamine wheal test as a simple and inexpensive test to detect the presence of topical steroids in fairness cream.

局部用皮质类固醇（TC）滥用是一个普遍存在的全球性问题。最近出现的一个令人担忧的问题是美白面霜中掺假的TC。通过高效液相色谱法（HPLC）可以检测出美白化妆品面霜中是否存在TC。由于HPLC价格昂贵、耗时且不易获得，我们建议使用组胺风团试验作为一种简单且廉价的检测方法，来检测美白面霜中是否存在局部用类固醇。