• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一组结直肠癌患者的流行病学和临床特征

Epidemiological and Clinical Aspects in a Cohort of Colorectal Cancer Patients.

作者信息

Ciobanu Alina Elena, Marginean Cristina Maria, Mesina Cristian, Balseanu Tudor-Adrian, Ciobanu Daniela, Florescu Mirela Marinela

机构信息

PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.

Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2024 Jan-Mar;50(1):106-116. doi: 10.12865/CHSJ.50.01.14. Epub 2024 Mar 31.

DOI:10.12865/CHSJ.50.01.14
PMID:38846472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11151939/
Abstract

We conducted a retrospective, observational study, based on 91 patients diagnosed with colorectal cancer (CRC), hospitalized and evaluated within the Surgical and the 2nd Internal Medicine Clinic, the Clinical Emergency County Hospital Craiova, between October 2020 and October 2022. We aimed in this study to analyze the epidemiological aspects and clinical characteristics of patients with CRC. In our study group, the patients' ages were between 30-89 years, with mean a of 68.06 (±9.39) years. The incidence of CRC cases in young patients was relatively low. 56.04% of all patients lived in urban areas. In 57.14% of cases, tumors were found on the left colon. The histopathological (HP) examination revealed the net predominance of adenocarcinoma. Depending on the HP grade, the tumor formations were represented predominantly by moderate and poorly differentiated tumors, having G2 and G3 grades. The T3 tumors predominated the total tumors identified. We observed that obstructions have the highest percentages on the left colon, while haemorrhages and perforations have higher percentages on the right side of the colon. The results obtained in our study largely validated the hypothesis proposed at the beginning of the study, according to which, using the clinical, paraclinical, and HP data, we can create a typology of the patient with CRC, from the Craiova Reference Center, to guide us in identifying some measures to decrease the percentage of CRC, as well as to improve the efficiency of the surgical treatment for these cases.

摘要

我们进行了一项回顾性观察研究,该研究基于2020年10月至2022年10月期间在克拉约瓦县临床急诊医院外科和第二内科诊所住院并接受评估的91例诊断为结直肠癌(CRC)的患者。我们在本研究中的目的是分析CRC患者的流行病学方面和临床特征。在我们的研究组中,患者年龄在30 - 89岁之间,平均年龄为68.06(±9.39)岁。年轻患者中CRC病例的发生率相对较低。所有患者中有56.04%生活在城市地区。在57.14%的病例中,肿瘤发现于左半结肠。组织病理学(HP)检查显示腺癌占主导。根据HP分级,肿瘤形成主要以中度和低分化肿瘤为主,为G2和G3级。T3肿瘤在所有确定的肿瘤中占主导。我们观察到梗阻在左半结肠的百分比最高,而出血和穿孔在结肠右侧的百分比更高。我们研究中获得的结果在很大程度上验证了研究开始时提出的假设,即根据该假设,利用临床、辅助检查和HP数据,我们可以创建来自克拉约瓦参考中心的CRC患者分类,以指导我们确定一些降低CRC百分比的措施,以及提高这些病例手术治疗的效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/7c6b63e7e608/CHSJ-50-01-106-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/cbf1c0e1361f/CHSJ-50-01-106-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/1d3a0d5d0c4a/CHSJ-50-01-106-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/a5d1e4fa3efd/CHSJ-50-01-106-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/a946b1ab232d/CHSJ-50-01-106-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/42c4a6ca12cb/CHSJ-50-01-106-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/4f77da12acee/CHSJ-50-01-106-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/7c6b63e7e608/CHSJ-50-01-106-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/cbf1c0e1361f/CHSJ-50-01-106-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/1d3a0d5d0c4a/CHSJ-50-01-106-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/a5d1e4fa3efd/CHSJ-50-01-106-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/a946b1ab232d/CHSJ-50-01-106-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/42c4a6ca12cb/CHSJ-50-01-106-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/4f77da12acee/CHSJ-50-01-106-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1274/11151939/7c6b63e7e608/CHSJ-50-01-106-fig7.jpg

相似文献

1
Epidemiological and Clinical Aspects in a Cohort of Colorectal Cancer Patients.一组结直肠癌患者的流行病学和临床特征
Curr Health Sci J. 2024 Jan-Mar;50(1):106-116. doi: 10.12865/CHSJ.50.01.14. Epub 2024 Mar 31.
2
Epidemiological, Clinical and Biological Hemogram Features in a Cohort of Neuroendocrine Tumor Patients.一组神经内分泌肿瘤患者的流行病学、临床和生物学血常规特征
Curr Health Sci J. 2024 Apr-Jun;50(2):256-266. doi: 10.12865/CHSJ.50.02.11. Epub 2024 Jun 30.
3
Colorectal cancer - clinical and morphological aspects.结直肠癌——临床与形态学方面
Rom J Morphol Embryol. 2014;55(1):103-10.
4
Grades of Poorly Differentiated Clusters are Associated with Lymph Node and the Tumour, Node and Metastasis Stages in Colorectal Carcinoma.低分化簇分级与结直肠癌的淋巴结及肿瘤、淋巴结转移分期相关。
Malays J Med Sci. 2023 Dec;30(6):70-78. doi: 10.21315/mjms2023.30.6.8. Epub 2023 Dec 19.
5
Fecal occult blood test for colorectal cancer screening: an evidence-based analysis.用于结直肠癌筛查的粪便潜血试验:一项基于证据的分析。
Ont Health Technol Assess Ser. 2009;9(10):1-40. Epub 2009 Sep 1.
6
Contributions of Adenocarcinoma and Carcinoid Tumors to Early-Onset Colorectal Cancer Incidence Rates in the United States.腺癌和类癌肿瘤对美国早发性结直肠癌发病率的贡献。
Ann Intern Med. 2021 Feb;174(2):157-166. doi: 10.7326/M20-0068. Epub 2020 Dec 15.
7
EARLY-ONSET COLORECTAL CANCER: AN ELEVEN-YEAR ANALYSIS OF CLINICOPATHOLOGICAL CHARACTERISTICS AT A TERTIARY HEALTHCARE CENTER.早发性结直肠癌:一家三级医疗机构十一年临床病理特征分析。
Arq Gastroenterol. 2023 Jul-Sep;60(3):315-321. doi: 10.1590/S0004-2803.230302023-23.
8
Histopathology analysis of benign colorectal diseases and colorectal cancer in Hatyai Hospital, Songkhla, Thailand.泰国宋卡府合艾医院良性结直肠疾病与结直肠癌的组织病理学分析
Asian Pac J Cancer Prev. 2013;14(4):2667-71. doi: 10.7314/apjcp.2013.14.4.2667.
9
Clinical, histopathological and immunohistochemical features of brain metastases originating in colorectal cancer: a series of 27 consecutive cases.结直肠癌脑转移的临床、组织病理学和免疫组织化学特征:连续 27 例病例系列。
Rom J Morphol Embryol. 2020;61(1):81-93. doi: 10.47162/RJME.61.1.09.
10
Left-sided location is a risk factor for lymph node metastasis of T1 colorectal cancer: a single-center retrospective study.左侧部位是T1期结直肠癌淋巴结转移的危险因素:一项单中心回顾性研究。
Int J Colorectal Dis. 2020 Oct;35(10):1911-1919. doi: 10.1007/s00384-020-03668-x. Epub 2020 Jun 16.

引用本文的文献

1
Clinical Outcome Differences in Mucinous Versus Non-Mucinous Colonic Adenocarcinoma: A Comparative Study.黏液性与非黏液性结肠腺癌的临床结局差异:一项比较研究。
Diagnostics (Basel). 2025 Jan 15;15(2):192. doi: 10.3390/diagnostics15020192.

本文引用的文献

1
Clinicopathological Analysis of Complicated Colorectal Cancer: A Five-Year Retrospective Study from a Single Surgery Unit.复杂性结直肠癌的临床病理分析:来自单一外科单元的五年回顾性研究
Diagnostics (Basel). 2023 Jun 9;13(12):2016. doi: 10.3390/diagnostics13122016.
2
The Challenges of Colorectal Cancer Surgery during the COVID-19 Pandemic in Romania: A Three-Year Retrospective Study.罗马尼亚 COVID-19 大流行期间结直肠癌手术面临的挑战:一项为期三年的回顾性研究。
Int J Environ Res Public Health. 2022 Nov 2;19(21):14320. doi: 10.3390/ijerph192114320.
3
The Impact of the COVID-19 Pandemic on Colorectal Cancer Patients in a Tertiary Center in Romania. Single Center Retrospective Study.
罗马尼亚一家三级中心的 COVID-19 大流行对结直肠癌患者的影响。单中心回顾性研究。
Chirurgia (Bucur). 2022 Feb;117(1):45-54. doi: 10.21614/chirurgia.2611.
4
The ever-increasing importance of cancer as a leading cause of premature death worldwide.癌症作为全球范围内导致过早死亡的主要原因,其重要性日益增加。
Cancer. 2021 Aug 15;127(16):3029-3030. doi: 10.1002/cncr.33587. Epub 2021 Jun 4.
5
Different disease characteristics in young patients with colorectal cancer: a large retrospective study in a city in Romania.罗马尼亚某城市年轻结直肠癌患者的不同疾病特征:一项大型回顾性研究
J Int Med Res. 2021 May;49(5):3000605211016630. doi: 10.1177/03000605211016630.
6
Cancer statistics for the year 2020: An overview.2020年癌症统计数据概述。
Int J Cancer. 2021 Apr 5. doi: 10.1002/ijc.33588.
7
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
8
Global Burden of 5 Major Types of Gastrointestinal Cancer.全球 5 大常见胃肠道癌症负担
Gastroenterology. 2020 Jul;159(1):335-349.e15. doi: 10.1053/j.gastro.2020.02.068. Epub 2020 Apr 2.
9
Colorectal Cancer Trends of 2018 in Romania-an Important Geographical Variation Between Northern and Southern Lands and High Mortality Versus European Averages.2018 年罗马尼亚结直肠癌趋势——北部和南部地区存在重要的地理差异,死亡率高于欧洲平均水平。
J Gastrointest Cancer. 2021 Mar;52(1):222-228. doi: 10.1007/s12029-020-00382-3.
10
Colorectal cancer statistics, 2020.2020 年结直肠癌统计数据。
CA Cancer J Clin. 2020 May;70(3):145-164. doi: 10.3322/caac.21601. Epub 2020 Mar 5.