Ciobanu Alina Elena, Marginean Cristina Maria, Mesina Cristian, Balseanu Tudor-Adrian, Ciobanu Daniela, Florescu Mirela Marinela
PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.
Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania.
Curr Health Sci J. 2024 Jan-Mar;50(1):106-116. doi: 10.12865/CHSJ.50.01.14. Epub 2024 Mar 31.
We conducted a retrospective, observational study, based on 91 patients diagnosed with colorectal cancer (CRC), hospitalized and evaluated within the Surgical and the 2nd Internal Medicine Clinic, the Clinical Emergency County Hospital Craiova, between October 2020 and October 2022. We aimed in this study to analyze the epidemiological aspects and clinical characteristics of patients with CRC. In our study group, the patients' ages were between 30-89 years, with mean a of 68.06 (±9.39) years. The incidence of CRC cases in young patients was relatively low. 56.04% of all patients lived in urban areas. In 57.14% of cases, tumors were found on the left colon. The histopathological (HP) examination revealed the net predominance of adenocarcinoma. Depending on the HP grade, the tumor formations were represented predominantly by moderate and poorly differentiated tumors, having G2 and G3 grades. The T3 tumors predominated the total tumors identified. We observed that obstructions have the highest percentages on the left colon, while haemorrhages and perforations have higher percentages on the right side of the colon. The results obtained in our study largely validated the hypothesis proposed at the beginning of the study, according to which, using the clinical, paraclinical, and HP data, we can create a typology of the patient with CRC, from the Craiova Reference Center, to guide us in identifying some measures to decrease the percentage of CRC, as well as to improve the efficiency of the surgical treatment for these cases.
我们进行了一项回顾性观察研究,该研究基于2020年10月至2022年10月期间在克拉约瓦县临床急诊医院外科和第二内科诊所住院并接受评估的91例诊断为结直肠癌(CRC)的患者。我们在本研究中的目的是分析CRC患者的流行病学方面和临床特征。在我们的研究组中,患者年龄在30 - 89岁之间,平均年龄为68.06(±9.39)岁。年轻患者中CRC病例的发生率相对较低。所有患者中有56.04%生活在城市地区。在57.14%的病例中,肿瘤发现于左半结肠。组织病理学(HP)检查显示腺癌占主导。根据HP分级,肿瘤形成主要以中度和低分化肿瘤为主,为G2和G3级。T3肿瘤在所有确定的肿瘤中占主导。我们观察到梗阻在左半结肠的百分比最高,而出血和穿孔在结肠右侧的百分比更高。我们研究中获得的结果在很大程度上验证了研究开始时提出的假设,即根据该假设,利用临床、辅助检查和HP数据,我们可以创建来自克拉约瓦参考中心的CRC患者分类,以指导我们确定一些降低CRC百分比的措施,以及提高这些病例手术治疗的效率。