School of Information and Engineering, Dalarna University, Falun, Sweden.
School of Health and Welfare, Dalarna University, Falun, Sweden.
J Alzheimers Dis. 2024;100(1):1-27. doi: 10.3233/JAD-231459.
Dementia is a general term for several progressive neurodegenerative disorders including Alzheimer's disease. Timely and accurate detection is crucial for early intervention. Advancements in artificial intelligence present significant potential for using machine learning to aid in early detection.
Summarize the state-of-the-art machine learning-based approaches for dementia prediction, focusing on non-invasive methods, as the burden on the patients is lower. Specifically, the analysis of gait and speech performance can offer insights into cognitive health through clinically cost-effective screening methods.
A systematic literature review was conducted following the PRISMA protocol (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The search was performed on three electronic databases (Scopus, Web of Science, and PubMed) to identify the relevant studies published between 2017 to 2022. A total of 40 papers were selected for review.
The most common machine learning methods employed were support vector machine followed by deep learning. Studies suggested the use of multimodal approaches as they can provide comprehensive and better prediction performance. Deep learning application in gait studies is still in the early stages as few studies have applied it. Moreover, including features of whole body movement contribute to better classification accuracy. Regarding speech studies, the combination of different parameters (acoustic, linguistic, cognitive testing) produced better results.
The review highlights the potential of machine learning, particularly non-invasive approaches, in the early prediction of dementia. The comparable prediction accuracies of manual and automatic speech analysis indicate an imminent fully automated approach for dementia detection.
痴呆症是几种进行性神经退行性疾病的统称,包括阿尔茨海默病。及时、准确的检测对于早期干预至关重要。人工智能的进步为使用机器学习辅助早期检测提供了巨大潜力。
总结基于机器学习的痴呆症预测的最新方法,重点关注非侵入性方法,因为这种方法对患者的负担较低。具体来说,通过临床成本效益高的筛查方法分析步态和言语表现,可以深入了解认知健康状况。
按照 PRISMA 协议(系统评价和荟萃分析的首选报告项目)进行系统文献综述。在三个电子数据库(Scopus、Web of Science 和 PubMed)上进行了搜索,以确定 2017 年至 2022 年期间发表的相关研究。共选择了 40 篇论文进行综述。
最常用的机器学习方法是支持向量机,其次是深度学习。研究表明,使用多模态方法,因为它们可以提供全面和更好的预测性能。深度学习在步态研究中的应用仍处于早期阶段,因为很少有研究应用它。此外,包含全身运动特征有助于提高分类准确性。关于言语研究,结合不同参数(声学、语言学、认知测试)可以产生更好的结果。
综述强调了机器学习,特别是非侵入性方法,在痴呆症早期预测中的潜力。手动和自动语音分析的预测精度相当表明,即将出现一种完全自动化的痴呆症检测方法。