Stevanovic Dejan, Cirovic Nikola, Cortese Samuele, Knez Rajna, Kerekes Nóra
Psychiatry Department, Clinic for Neurology and Psychiatry for Children and Youth, Dr Subotic 6a, Belgrade, 11000, Serbia.
Department of Psychology, Faculty of Philosophy, University of Nis, Nis, Serbia.
Eur Child Adolesc Psychiatry. 2025 Jan;34(1):357-360. doi: 10.1007/s00787-024-02488-6. Epub 2024 Jun 7.
The coexistence of mental and physical health illnesses could be accounted for by an underlying general disease factor (termed d-factor), reflecting theoretical underpinnings based on possible genetic and pathophysiological overlapping mechanisms. This study evaluated whether the d-factor underlies mental and physical health illnesses in adolescents. A series of confirmatory factor analyses were conducted using data from 1120 adolescents. The proposed common underlying factor, we believe is the d-factor, was consistently present across different modeling approaches, including unidimensional, correlated-factor, and bifactor models. The best model fit was achieved with the bifactor model represented by mental, neurological, and psychical conditions tested. The first compelling evidence was provided supporting the existence of the transdiagnostic d-factor in youth, opening the door to innovative research of comorbid mental and physical health conditions.
心理健康问题与身体健康疾病的共存可能是由一个潜在的一般疾病因素（称为d因素）导致的，这反映了基于可能的遗传和病理生理重叠机制的理论基础。本研究评估了d因素是否是青少年心理健康问题和身体健康疾病的潜在因素。使用来自1120名青少年的数据进行了一系列验证性因素分析。我们认为所提出的共同潜在因素就是d因素，它在不同的建模方法中始终存在，包括单维模型、相关因素模型和双因素模型。在所测试的以精神、神经和心理状况为代表的双因素模型中，实现了最佳的模型拟合。本研究提供了首个有力证据，支持了青少年中跨诊断d因素的存在，为共病的心理健康和身体健康状况的创新性研究打开了大门。
