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Accuracy of the New Creatinine-based Equations for Estimating Glomerular Filtration Rate in Koreans.基于新的肌酐方程估算韩国人肾小球滤过率的准确性。
Ann Lab Med. 2023 May 1;43(3):244-252. doi: 10.3343/alm.2023.43.3.244. Epub 2022 Dec 22.
3
Prevalence of Dietary Supplement Use among Athletes Worldwide: A Scoping Review.全球运动员补充剂使用的流行率:一项范围综述。
Nutrients. 2022 Oct 3;14(19):4109. doi: 10.3390/nu14194109.
4
Epidemiology of chronic kidney disease: an update 2022.慢性肾脏病流行病学:2022年最新情况
Kidney Int Suppl (2011). 2022 Apr;12(1):7-11. doi: 10.1016/j.kisu.2021.11.003. Epub 2022 Mar 18.
5
Nutritional and Non-Nutritional Strategies in Bodybuilding: Impact on Kidney Function.健美运动中的营养和非营养策略:对肾功能的影响。
Int J Environ Res Public Health. 2022 Apr 3;19(7):4288. doi: 10.3390/ijerph19074288.
6
Adverse effects associated with use of specific dietary supplements: The US Military Dietary Supplement Use Study.与特定膳食补充剂使用相关的不良反应:美国军事膳食补充剂使用研究。
Food Chem Toxicol. 2022 Mar;161:112840. doi: 10.1016/j.fct.2022.112840. Epub 2022 Jan 31.
7
Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?关于肌酸补充的常见问题和误解:科学证据到底显示了什么?
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8
Uric acid level and kidney function: a cross-sectional study of the Korean national health and nutrition examination survey (2016-2017).尿酸水平与肾功能:韩国国家健康和营养检查调查(2016-2017 年)的横断面研究。
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9
Whey protein supplementation and its potentially adverse effects on health: a systematic review.乳清蛋白补充剂及其对健康的潜在不良影响:一项系统综述。
Appl Physiol Nutr Metab. 2021 Jan;46(1):27-33. doi: 10.1139/apnm-2020-0370. Epub 2020 Jul 23.
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Acute kidney injury.急性肾损伤。
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一名男性运动员肌酐和尿酸持续升高:病例报告。

Continued elevation of creatinine and uric acid in a male athlete: A case report.

作者信息

Alaseem Ali M

机构信息

Department of Pharmacology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.

出版信息

SAGE Open Med Case Rep. 2024 Jun 9;12:2050313X241260229. doi: 10.1177/2050313X241260229. eCollection 2024.

DOI:10.1177/2050313X241260229
PMID:38859872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11163930/
Abstract

Whey protein and other protein-fortified supplements are frequently consumed as nutritional supplements to aid in muscle hypertrophy and myogenesis. This case presents a 36-year-old athletic male with elevated creatinine and uric acid levels during routine laboratory evaluation. The patient had no history of kidney disease, diabetes, or hypertension. It was revealed that the patient had been regularly consuming whey protein as a dietary supplement for 2 months. Given the potential association between the elevated creatinine and uric acid levels and the use of whey protein, the patient was advised to discontinue the supplement. The patient then switched to protein-fortified milk to mitigate the possible harmful connection between the dietary intake and the laboratory findings. However, despite the dietary change, the increased levels of creatinine and uric acid persisted. This observation suggests that the elevated levels may be attributed to chronic whey protein consumption along with high-protein dietary consumption.

摘要

乳清蛋白和其他蛋白质强化补充剂经常作为营养补充剂食用,以帮助肌肉肥大和肌生成。该病例为一名36岁的男性运动员,在常规实验室检查中肌酐和尿酸水平升高。该患者无肾脏疾病、糖尿病或高血压病史。结果显示,该患者作为膳食补充剂定期食用乳清蛋白已有2个月。鉴于肌酐和尿酸水平升高与乳清蛋白使用之间的潜在关联,建议患者停止服用该补充剂。然后,患者改用蛋白质强化牛奶,以减轻饮食摄入与实验室检查结果之间可能存在的有害联系。然而,尽管饮食有所改变,肌酐和尿酸水平仍持续升高。这一观察结果表明,水平升高可能归因于长期食用乳清蛋白以及高蛋白饮食。