Panigrahy Uttam Prasad, Buchade Rahul Subhash, Subhadra Sandhya, Narayanan Anoop Kumar, Gunjal Sachinkumar Dnyaneshwar, Selvakumari Ezhilarasan, Pandey Narendra Kumar, Wal Ankita
Faculty of Pharmaceutical Science, Assam Downtown University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India.
SCES's Indira College of Pharmacy "Niramay", S.No.89/2A, New Pune Mumbai Highway, Tathwade, Pune, Maharashtra, India.
Curr Gene Ther. 2025;25(3):210-226. doi: 10.2174/0115665232291487240603093218.
Acetylresveratrol (AC-Res), to date, is a powerful stilbene phytoalexin generated organically or as a component of a plant's defensive system, is a significant plant phenolic chemical portion and is investigated as a therapy option for a number of disorders. Owing to its inadequate stabilisation and considerable conformation rigidity, the utility of AC-Res as a medication is limited.
The current review article outlined the structure of AC-Res, their methods of activity, and the latest technological progress in the administration of these molecules. It is conceivable to deduce that AC-Res has a variety of consequences for the cellular functions of infected cells.
The literature survey for the present article was gathered from the authentic data published by various peer-reviewed publishers employing Google Scholar and PubMedprioritizing Scopus and Web of Science indexed journals as the search platform focusing on AC-Res pharmacological actions, particularly in the English language.
Despite its extensive spectrum of biological and therapeutic applications, AC-Res has become a source of increasing concern. Depending on the researchers, AC-Res possesses radioprotective, cardioprotective, neurological, anti-inflammatory, and anti-microbial potential. It also has anti-cancer and antioxidant properties.
To avoid non-specific cytotoxicity, optimization efforts are presently emphasizing the possible usage of AC-Res based on nanocrystals, nanoparticles and dendrimers, and nanocrystals. Finally, while using AC-Res in biology is still a way off, researchers agree that if they continue to explore it, AC-Res and similar parts will be recognized as actual possibilities for a variety of things in the next years.
乙酰白藜芦醇（AC-Res）是一种强大的芪类植物抗毒素，迄今为止，它可通过有机方式生成或作为植物防御系统的一个组成部分，是一种重要的植物酚类化学成分，并且正在作为多种疾病的治疗选择进行研究。由于其稳定性不足和相当大的构象刚性，AC-Res作为药物的应用受到限制。
当前这篇综述文章概述了AC-Res的结构、其作用方式以及这些分子给药方面的最新技术进展。可以推断，AC-Res对受感染细胞的细胞功能有多种影响。
本文的文献调查收集自各种同行评审出版商发表的真实数据，使用谷歌学术和PubMed，优先选择Scopus和科学网索引的期刊作为搜索平台，重点关注AC-Res的药理作用，尤其是英文文献。
尽管AC-Res具有广泛的生物学和治疗应用，但它已成为越来越受关注的一个来源。根据研究人员的说法，AC-Res具有辐射防护、心脏保护、神经保护、抗炎和抗菌潜力。它还具有抗癌和抗氧化特性。
为避免非特异性细胞毒性，目前的优化工作着重于基于纳米晶体、纳米颗粒和树枝状大分子以及纳米晶体的AC-Res的可能用途。最后，虽然在生物学中使用AC-Res仍有很长的路要走，但研究人员一致认为，如果他们继续探索，AC-Res及类似成分在未来几年将被视为多种用途的实际可能性。
