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评估休克指数、修订的出血和输血评估(RABT)、血液消耗评估(ABC)和新型 PTTrauma 评分,以预测穿透性胸部创伤的关键输血阈值(CAT)。

Evaluating the Shock Index, Revised Assessment of Bleeding and Transfusion (RABT), Assessment of Blood Consumption (ABC) and novel PTTrauma score to predict critical transfusion threshold (CAT) in penetrating thoracic trauma.

机构信息

Department of Surgery, Universidad del Valle, Cl. 4B #36-00, El Sindicato, Cali Valle del Cauca, Cali, Colombia.

Department of Surgery and Clinical Research Center, Fundación Valle del Lili, Cali, Colombia.

出版信息

Sci Rep. 2024 Jun 11;14(1):13395. doi: 10.1038/s41598-024-62579-x.

Abstract

The shock index (SI) has been associated with predicting transfusion needs in trauma patients. However, its utility in penetrating thoracic trauma (PTTrauma) for predicting the Critical Administration Threshold (CAT) has not been well-studied. This study aimed to evaluate the prognostic value of SI in predicting CAT in PTTrauma patients and compare its performance with the Assessment of Blood Consumption (ABC) and Revised Assessment of Bleeding and Transfusion (RABT) scores. We conducted a prognostic type 2, single-center retrospective observational cohort study on patients with PTTrauma and an Injury Severity Score (ISS) > 9. The primary exposure was SI at admission, and the primary outcome was CAT. Logistic regression and decision curve analysis were used to assess the predictive performance of SI and the PTTrauma score, a novel model incorporating clinical variables. Of the 620 participants, 53 (8.5%) had more than one CAT. An SI > 0.9 was associated with CAT (adjusted OR 4.89, 95% CI 1.64-14.60). The PTTrauma score outperformed SI, ABC, and RABT scores in predicting CAT (AUC 0.867, 95% CI 0.826-0.908). SI is a valuable predictor of CAT in PTTrauma patients. The novel PTTrauma score demonstrates superior performance compared to existing scores, highlighting the importance of developing targeted predictive models for specific injury patterns. These findings can guide clinical decision-making and resource allocation in the management of PTTrauma.

摘要

休克指数 (SI) 与预测创伤患者输血需求相关。然而,其在预测穿透性胸外伤 (PTTrauma) 中的关键输血阈值 (CAT) 方面的应用尚未得到充分研究。本研究旨在评估 SI 在预测 PTTrauma 患者 CAT 中的预后价值,并比较其与评估血液消耗 (ABC) 和修订的出血和输血评估 (RABT) 评分的性能。我们对创伤严重度评分 (ISS) > 9 的 PTTrauma 患者进行了一项预后型 2 型、单中心回顾性观察队列研究。主要暴露为入院时的 SI,主要结局为 CAT。我们使用逻辑回归和决策曲线分析来评估 SI 和 PTTrauma 评分(一种纳入临床变量的新型模型)的预测性能。在 620 名参与者中,有 53 名(8.5%)患者有多个 CAT。SI > 0.9 与 CAT 相关(调整后的 OR 4.89,95%CI 1.64-14.60)。PTTrauma 评分在预测 CAT 方面优于 SI、ABC 和 RABT 评分(AUC 0.867,95%CI 0.826-0.908)。SI 是 PTTrauma 患者 CAT 的有价值预测指标。新型 PTTrauma 评分与现有评分相比表现出更好的性能,突出了为特定损伤模式开发针对性预测模型的重要性。这些发现可以指导 PTTrauma 管理中的临床决策和资源分配。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3c7/11166957/eadaabeb05bf/41598_2024_62579_Fig1_HTML.jpg

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