Lv Tianxing, Zhan Chengfang, Pan Qianqian, Xu Haorong, Fang Hongda, Wang Mengcen, Matsumoto Haruna
State Key Laboratory of Rice Biology & Ministry of Agricultural and Rural Affairs Laboratory of Molecular Biology of Crop Pathogens and Insects Zhejiang University Hangzhou China.
Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Institute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology Zhejiang University Hangzhou China.
Imeta. 2023 Jul 16;2(3):e129. doi: 10.1002/imt2.129. eCollection 2023 Aug.
Single pathogen-targeted disease management measure has shown drawbacks in field efficacy under the scenario of global change. An in-depth understanding of plant pathogenesis will provide a promising solution but faces the challenges of the emerging paradigm involving the plant microbiome. While the beneficial impact of the plant microbiome is well characterized, their potential role in facilitating pathological processes has so far remained largely overlooked. To address these unsolved controversies and emerging challenges, we hereby highlight the pathobiome, the disease-assisting portion hidden in the plant microbiome, in the plant pathogenesis paradigm. We review the detrimental actions mediated by the pathobiome at multiple scales and further discuss how natural and human triggers result in the prevalence of the plant pathobiome, which would probably provide a clue to the mitigation of plant disease epidemics. Collectively, the article would advance the current insight into plant pathogenesis and also pave a new way to cope with the upward trends of plant disease by designing the pathobiome-targeted measure.
在全球变化的背景下，单一病原体靶向疾病管理措施在田间效果方面已显现出弊端。深入了解植物发病机制将提供一个有前景的解决方案，但面临着涉及植物微生物组的新兴范式的挑战。虽然植物微生物组的有益影响已得到充分表征，但其在促进病理过程中的潜在作用迄今为止在很大程度上仍被忽视。为了解决这些未解决的争议和新出现的挑战，我们在此强调植物发病机制范式中的病理生物群落，即隐藏在植物微生物组中的疾病辅助部分。我们回顾了病理生物群落在多个尺度上介导的有害作用，并进一步讨论了自然和人为触发因素如何导致植物病理生物群落的流行，这可能为减轻植物病害流行提供线索。总体而言，本文将推进当前对植物发病机制的认识，并通过设计针对病理生物群落的措施，为应对植物病害上升趋势开辟一条新途径。
