Javid M J
J Neurosurg. 1985 May;62(5):662-6. doi: 10.3171/jns.1985.62.5.0662.
A 9- to 12-year follow-up review was conducted in 105 of 124 patients who were treated with chymopapain chemonucleolysis for herniated lumbar disc. The data were obtained from responses to a questionnaire. Seventy-nine patients (75.2%) reported marked improvement, six (5.7%) had slight improvement, and 20 (19.0%) had no improvement. Of the 87 patients not receiving workman's compensation, 70 patients (80.5%) had marked improvement; four (4.6%) had slight improvement; and 13 (14.9%) had no improvement. Of the 18 compensation cases, nine patients (50.0%) had marked improvement; two patients (11.1%) had slight improvement; and seven patients (38.9%) had no improvement. These results are comparable to those reported for surgical discectomy, and confirm that chymopapain chemonucleolysis is an alternative to surgery.
对124例接受木瓜凝乳蛋白酶化学髓核溶解术治疗腰椎间盘突出症的患者中的105例进行了9至12年的随访复查。数据通过对问卷的回答获得。79例患者（75.2%）报告有明显改善，6例（5.7%）有轻微改善，20例（19.0%）无改善。在87例未获得工伤赔偿的患者中，70例（80.5%）有明显改善；4例（4.6%）有轻微改善；13例（14.9%）无改善。在18例赔偿病例中，9例患者（50.0%）有明显改善；2例患者（11.1%）有轻微改善；7例患者（38.9%）无改善。这些结果与手术椎间盘切除术报告的结果相当，并证实木瓜凝乳蛋白酶化学髓核溶解术是手术的一种替代方法。
