Lad Urvi M, Dave Dhruti J, Desai Bhumi N, Suthar Devesh H, Modi Chetan K
Applied Chemistry Department, Faculty of Technology & Engineering, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390001, India.
Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, 390002, India.
J Fluoresc. 2025 May;35(5):3577-3587. doi: 10.1007/s10895-024-03799-2. Epub 2024 Jun 13.
In this study, we present an economical and efficient synthesis method for carbon nanodots (CNDs) derived from cinnamon bark wood powder, with the incorporation of L-arginine as a dopant at varying ratios (Cinnamon : L-Arginine - 1:0.25, 1:0.5) via a hydrothermal reaction. Extensive structural and optical characterization was conducted through techniques such as FTIR, XRD, HR-TEM, DLS, UV-Vis, and PL spectra, providing a comprehensive understanding of the properties of CNDs and doped-CNDs. Quantum yields (QY) were quantified for synthesized materials, contributing to the assessment of their fluorescence efficiency. The synthesized CNDs were successfully applied for bioimaging of yeast cells, employing fluorescence microscopy to visualize their interaction. Remarkably, L-arginine-doped CNDs exhibited enhanced fluorescence, showcasing the influence of the dopant. The nature of these CNDs was rigorously investigated, confirming their biocompatibility. Notably, this work presents a novel approach to synthesizing CNDs from a renewable and sustainable source, cinnamon bark wood powder, while exploring the effects of L-arginine doping on their optical and biological properties. This work not only contributes to the synthesis and characterization of CNDs but also highlights their potential for diverse applications, emphasizing their structural, optical, and biological attributes. The findings underscore the versatility of CNDs derived from cinnamon bark wood powder and their potential for advancing biotechnological and imaging applications.
在本研究中，我们提出了一种经济高效的合成方法，用于从肉桂树皮木粉中制备碳纳米点（CNDs），通过水热反应以不同比例（肉桂：L-精氨酸 - 1:0.25、1:0.5）掺入L-精氨酸作为掺杂剂。通过傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、高分辨透射电子显微镜（HR-TEM）、动态光散射（DLS）、紫外可见光谱（UV-Vis）和光致发光光谱（PL）等技术进行了广泛的结构和光学表征，从而全面了解了CNDs和掺杂CNDs的性质。对合成材料的量子产率（QY）进行了量化，有助于评估其荧光效率。合成的CNDs成功应用于酵母细胞的生物成像，利用荧光显微镜观察它们的相互作用。值得注意的是，L-精氨酸掺杂的CNDs表现出增强的荧光，展示了掺杂剂的影响。对这些CNDs的性质进行了严格研究，证实了它们的生物相容性。值得注意的是，这项工作提出了一种从可再生和可持续来源肉桂树皮木粉合成CNDs的新方法，同时探索了L-精氨酸掺杂对其光学和生物学性质的影响。这项工作不仅有助于CNDs的合成和表征，还突出了它们在各种应用中的潜力，强调了它们的结构、光学和生物学特性。研究结果强调了源自肉桂树皮木粉的CNDs的多功能性及其在推进生物技术和成像应用方面的潜力。
