University of North Carolina Greensboro, Department of Kinesiology, Greensboro, NC, USA.
Southeastern Louisiana University, Department of Kinesiology and Health Studies, Hammond, LA, USA.
Adv Neurobiol. 2024;35:137-155. doi: 10.1007/978-3-031-45493-6_8.
This chapter will focus on the role exercise appears to have on activation and modulating factors within the central nervous system related to endogenous like opioids and its possible contribution to exercise-induced hypoalgesia. The implications for the exercise-mediated alterations of CNS activation factors related to opioids, specifically endorphins and enkephalins, will be presented. In this update, we discuss utilization of new technology and methods to monitor mechanisms of opioid involvement to suggest their contribution with exercise mediated hypoalgesia as well as their relationships to alterations of perceptions of pain and mood. Several special populations were included to suggest that not all individuals will respond to the exercise by mediating hypoalgesia. Factors that may confound the current understanding and suggestions from the recent literature will be presented as well as suggestions for future investigations.
本章将重点介绍运动对内源性阿片样物质等中枢神经系统激活和调节因子的作用，以及其对运动诱导镇痛的可能贡献。本文将介绍与阿片类物质（特别是内啡肽和脑啡肽）相关的中枢神经系统激活因子的运动介导改变的意义。在本更新中，我们讨论了利用新技术和方法来监测阿片类物质参与的机制，以表明它们对运动介导的镇痛作用的贡献，以及它们与疼痛和情绪感知改变的关系。还纳入了几个特殊人群，以表明并非所有个体都会通过介导镇痛来对运动做出反应。本文还介绍了可能混淆当前理解的因素以及来自最近文献的建议，并为未来的研究提供了建议。
