Bakka Havil Stephen Alexander, Babu Perumalla Karthik, Kutikuppala L V Simhachalam, Reddy M V Ramana, Varshitha Golla
Department of General Surgery, Ramesh Sanghamitra Hospitals, Ongole 523001, Andhra Pradesh, India.
Department of General Surgery, Dr NTR University of Health Sciences, Vijayawada, Andhra Pradesh, India.
Int J Surg Case Rep. 2024 Jul;120:109881. doi: 10.1016/j.ijscr.2024.109881. Epub 2024 Jun 6.
Purtscher retinopathy is the rare form of occlusive microvasculopathy, characterized by multiple retinal white areas around the optic nerve head and fovea with paravascular clearing and may be related to intraretinal hemorrhages. Acute Pancreatitis (AP) is one of the most common gastrointestinal reasons for hospital admissions globally. The complications of Acute Pancreatitis may include Purtscher's-like retinopathy, which has a low incidence rate of less than 0.24 instances per million cases. This case report highlights the value of thorough medical history taking and examination, and it apprises the consideration of ophthalmological manifestation in patients of Acute Pancreatitis.
A 34-year-old female came to the emergency room due to intense abdominal pain associated with nausea and vomiting, which worsened over the last 24 h. The pain was described as continuous, sharp, and cramping-like in the upper abdomen, radiating to the back. Lab tests revealed elevated serum amylase and lipase levels, indicating pancreatitis, along with slight leukocytosis. A contrast-enhanced CT scan confirmed acute pancreatitis with mild inflammation and enlargement of the pancreas. Two days after admission, the patient experienced a sudden and painless loss of central vision in both eyes. There was no history of trauma or any other significant relevant history, other than pancreatitis. The ophthalmologist's examination found reduced visual acuity (6/60 in the right eye, 3/60 in the left eye), normal corneas, and anterior chambers.
Inkeles and Walsh established the first link between acute pancreatitis and Purtscher-like retinopathy when they reported three cases of the distinctive retinal appearance in individuals with acute pancreatitis in 1975.
The recovery and prognosis in cases of Purtscher-like retinopathy is variable and further research is required to ascertain the usage of corticosteroids and pentoxifylline in improving the course of a patient's with Purtscher's-like retinopathy.
普尔夏视网膜病变是一种罕见的闭塞性微血管病变形式,其特征为视神经乳头和黄斑周围出现多个视网膜白色区域,并伴有血管旁透亮区,且可能与视网膜内出血有关。急性胰腺炎(AP)是全球住院治疗最常见的胃肠道病因之一。急性胰腺炎的并发症可能包括类普尔夏视网膜病变,其发病率较低,每百万病例中少于0.24例。本病例报告强调了详细询问病史和进行检查的重要性,并提醒临床医生在急性胰腺炎患者中要考虑眼部表现。
一名34岁女性因剧烈腹痛伴恶心、呕吐前来急诊室,症状在过去24小时内加重。疼痛被描述为上腹部持续、尖锐的绞痛样疼痛,并放射至背部。实验室检查显示血清淀粉酶和脂肪酶水平升高,提示胰腺炎,同时伴有轻度白细胞增多。增强CT扫描证实为急性胰腺炎,胰腺有轻度炎症和肿大。入院两天后,患者双眼突然无痛性中心视力丧失。除胰腺炎外,无外伤史或其他任何重大相关病史。眼科医生检查发现视力下降(右眼6/60,左眼3/60),角膜和前房正常。
1975年,英克尔斯和沃尔什报告了3例急性胰腺炎患者出现独特视网膜表现的病例,首次建立了急性胰腺炎与类普尔夏视网膜病变之间的联系。
类普尔夏视网膜病变病例的恢复情况和预后各不相同,需要进一步研究以确定皮质类固醇和己酮可可碱在改善类普尔夏视网膜病变患者病程中的应用。