Oon Ming Liang, Wu Bingcheng, Lim Rachel, Liew Melvin Kang Ming, Petersson Fredrik
Department of Pathology, National University Hospital, Singapore, Singapore.
Department of Dentistry, Ng Teng Fong General Hospital, Singapore, Singapore.
Virchows Arch. 2025 Mar;486(3):617-620. doi: 10.1007/s00428-024-03850-4. Epub 2024 Jun 14.
Adult rhabdomyoma is an uncommon benign mesenchymal neoplasm that most often occurs in the head and neck. We present a 70 year-old male with a swelling on the floor of the mouth. Subsequent excision of the tumor revealed a hitherto undescribed morphological variant of this tumor that features a predominance of clear cells, which on light microscopy may mimic other other clear cell tumours of the head and neck region. We perform an in-depth analysis of the morphological and immunohistochemical features of this tumor, as well as discuss pitfalls in the diagnosis of this tumor and its differential diagnosis in the head and neck region.
成人横纹肌瘤是一种罕见的良性间叶性肿瘤，最常发生于头颈部。我们报告一例70岁男性，其口底有一肿物。随后切除的肿瘤显示出一种迄今未描述过的形态学变异型，其特征为透明细胞占优势，在光学显微镜下可能会与头颈部其他透明细胞肿瘤相混淆。我们对该肿瘤的形态学和免疫组化特征进行了深入分析，并讨论了该肿瘤诊断中的陷阱及其在头颈部的鉴别诊断。
