Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN 37996, USA.
Int J Mol Sci. 2024 May 29;25(11):5959. doi: 10.3390/ijms25115959.
Microbial foodborne pathogens present significant challenges to public health and the food industry, requiring rapid and accurate detection methods to prevent infections and ensure food safety. Conventional single biosensing techniques often exhibit limitations in terms of sensitivity, specificity, and rapidity. In response, there has been a growing interest in multimodal biosensing approaches that combine multiple sensing techniques to enhance the efficacy, accuracy, and precision in detecting these pathogens. This review investigates the current state of multimodal biosensing technologies and their potential applications within the food industry. Various multimodal biosensing platforms, such as opto-electrochemical, optical nanomaterial, multiple nanomaterial-based systems, hybrid biosensing microfluidics, and microfabrication techniques are discussed. The review provides an in-depth analysis of the advantages, challenges, and future prospects of multimodal biosensing for foodborne pathogens, emphasizing its transformative potential for food safety and public health. This comprehensive analysis aims to contribute to the development of innovative strategies for combating foodborne infections and ensuring the reliability of the global food supply chain.
微生物食源性致病菌对公共卫生和食品工业构成重大挑战,需要快速准确的检测方法来预防感染并确保食品安全。传统的单一生物传感技术在灵敏度、特异性和速度方面常常存在局限性。因此,人们越来越关注多模态生物传感方法,这些方法结合了多种传感技术,以提高检测这些病原体的效果、准确性和精度。本综述调查了多模态生物传感技术的现状及其在食品工业中的潜在应用。讨论了各种多模态生物传感平台,如光电化学、光学纳米材料、多种基于纳米材料的系统、混合生物传感微流控和微制造技术。该综述深入分析了多模态生物传感在食源性致病菌检测方面的优势、挑战和未来前景,强调了其对食品安全和公共卫生的变革潜力。这项全面分析旨在为打击食源性感染和确保全球食品供应链的可靠性提供创新策略的发展。