Department of Pharmacy, University of Pisa, Via Bonanno Pisano 6, 56126 Pisa, PI, Italy.
Teregroup Srl, Via David Livingstone 37, 41122 Modena, MO, Italy.
Nutrients. 2024 Jun 3;16(11):1752. doi: 10.3390/nu16111752.
, commonly known as , is a photosynthetic filamentous cyanobacterium (blue-green microalga) that has been utilized as a food source since ancient times. More recently, it has gained significant popularity as a dietary supplement due to its rich content of micro- and macro-nutrients. Of particular interest is a water soluble phycobiliprotein derived from known as phycocyanin C (C-PC), which stands out as the most abundant protein in this cyanobacterium. C-PC is a fluorescent protein, with its chromophore represented by the tetrapyrrole molecule phycocyanobilin B (PCB-B). While C-PC is commonly employed in food for its coloring properties, it also serves as the molecular basis for numerous nutraceutical features associated with . Indeed, the comprehensive C-PC, and to some extent, the isolated PCB-B, has been linked to various health-promoting effects. These benefits encompass conditions triggered by oxidative stress, inflammation, and other pathological conditions. The present review focuses on the bio-pharmacological properties of these molecules, positioning them as promising agents for potential new applications in the expanding nutraceutical market.
，通常被称为 ，是一种光合丝状蓝藻（蓝绿微藻），自古以来一直被用作食物来源。最近，由于其富含微量和常量营养素，它作为膳食补充剂变得非常受欢迎。特别值得关注的是一种来自 的水溶性藻胆蛋白，称为藻蓝蛋白 C（C-PC），它是这种蓝藻中最丰富的蛋白质。C-PC 是一种荧光蛋白，其发色团由四吡咯分子藻蓝胆素 B（PCB-B）表示。虽然 C-PC 通常因其着色特性而在食品中使用，但它也是与 相关的许多营养特性的分子基础。事实上，全面的 C-PC，在某种程度上，还有分离的 PCB-B，与各种促进健康的作用有关。本综述重点介绍了这些分子的生物药理学特性，将它们定位为在不断扩大的营养保健品市场中具有潜在新应用的有前途的药物。
