Department of Electrical & Computer Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Department of Chemical Engineering, College of Engineering, Jazan University, Jazan 45142, Saudi Arabia.
Molecules. 2024 May 22;29(11):2439. doi: 10.3390/molecules29112439.
The measurement of glucose concentration is a fundamental daily care for diabetes patients, and therefore, its detection with accuracy is of prime importance in the field of health care. In this study, the fabrication of an electrochemical sensor for glucose sensing was successfully designed. The electrode material was fabricated using polyaniline and systematically characterized using scanning electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and UV-visible spectroscopy. The polyaniline nanofiber-modified electrode showed excellent detection ability for glucose with a linear range of 10 μM to 1 mM and a detection limit of 10.6 μM. The stability of the same electrode was tested for 7 days. The electrode shows high sensitivity for glucose detection in the presence of interferences. The polyaniline-modified electrode does not affect the presence of interferences and has a low detection limit. It is also cost-effective and does not require complex sample preparation steps. This makes it a potential tool for glucose detection in pharmacy and medical diagnostics.
葡萄糖浓度的测量是糖尿病患者日常护理的基础,因此,其在医疗保健领域的精确检测至关重要。本研究成功设计了一种用于葡萄糖感测的电化学传感器。使用聚苯胺制造电极材料,并通过扫描电子显微镜、高分辨率透射电子显微镜、X 射线衍射、傅里叶变换红外光谱和紫外可见光谱对其进行了系统表征。聚苯胺纳米纤维修饰电极对葡萄糖具有出色的检测能力,线性范围为 10 μM 至 1 mM,检测限为 10.6 μM。还测试了相同电极的稳定性,结果表明其在 7 天内保持稳定。该电极在存在干扰的情况下对葡萄糖具有高灵敏度。聚苯胺修饰电极不影响干扰物的存在,并且具有较低的检测限。它还具有成本效益,并且不需要复杂的样品制备步骤。因此,它是药剂学和医学诊断中葡萄糖检测的潜在工具。