DBT-National Institute of Animal Biotechnology (NIAB), Hyderabad 500032, India.
DBT-Regional Centre for Biotechnology (RCB), Faridabad 121001, India.
Biosensors (Basel). 2022 May 26;12(6):365. doi: 10.3390/bios12060365.
Salmonellosis is a major cause of foodborne infections, caused by , posing a major health risk. It possesses the ability to infiltrate the food supply chain at any point throughout the manufacturing, distribution, processing or quality control process. infection has increased severely and requires effective and efficient methods for early monitoring and detection. Traditional methods, such as real-time polymerase chain reaction and culture plate, consume a lot of time and are labor-intensive. Therefore, new quick detection methods for on-field applications are urgently needed. Biosensors provide consumer-friendly approaches for quick on-field diagnoses. In the last few years, there has been a surge in research into the creation of reliable and advanced electrochemical sensors for the detection of strains in food samples. Electrochemical sensors provide extensive accuracy and reproducible results. Herein, we present a comprehensive overview of electrochemical sensors for the detection of by focusing on various mechanisms of electrochemical transducer. Further, we explain new-generation biosensors (microfluidics, CRISPR- and IOT-based) for point-of care applications. This review also highlights the limitations of developing biosensors in detection and future possibilities.
沙门氏菌病是食源性感染的主要原因,由沙门氏菌引起,对健康构成重大威胁。它有能力在制造、分销、加工或质量控制过程中的任何点渗透到食物链中。沙门氏菌感染严重加剧,需要有效的早期监测和检测方法。传统方法,如实时聚合酶链反应和培养平板,需要大量时间且劳动强度大。因此,迫切需要用于现场应用的新的快速检测方法。生物传感器为快速现场诊断提供了消费者友好的方法。在过去几年中,人们对用于检测食品样本中沙门氏菌菌株的可靠和先进电化学传感器的研究激增。电化学传感器提供广泛的准确性和可重复性结果。在此,我们通过聚焦各种电化学换能器的机制,全面概述了用于检测的电化学传感器。此外,我们还解释了用于即时护理应用的新一代生物传感器(微流控、基于 CRISPR 和物联网)。本综述还强调了开发生物传感器在沙门氏菌检测中的局限性和未来的可能性。