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外科医生的资历和专业兴趣对急诊剖腹手术后死亡率的影响:系统评价和荟萃分析。

Effect of surgeon's seniority and subspeciality interest on mortality after emergency laparotomy: A systematic review and meta-analysis.

机构信息

University of Leeds, Leeds, UK.

University of Cambridge, Cambridge, UK.

出版信息

Colorectal Dis. 2024 Aug;26(8):1495-1504. doi: 10.1111/codi.17079. Epub 2024 Jun 19.

DOI:10.1111/codi.17079
PMID:38898583
Abstract

AIM

To evaluate effect of surgeon's seniority (trainee surgeon vs. consultant surgeon) and surgeon's subspeciality interest on postoperative mortality in patients undergoing emergency laparotomy (EL).

METHOD

A systematic review was conducted and reported according to the Cochrane Handbook for Systematic Reviews and the PRISMA statement standards, respectively. We evaluated all studies comparing the risk of postoperative mortality in patients undergoing EL between (a) trainee surgeon and consultant surgeon, and (b) surgeon without and with subspeciality interest related to pathology. Random effects modelling was applied for the analyses. The certainty of evidence was assessed using the GRADE system.

RESULTS

Analysis of 256 844 patients from 13 studies showed no difference in the risk of postoperative mortality between trainee-led and consultant-led EL (OR: 0.76, p = 0.12). However, EL performed by a surgeon without subspeciality interest related to the pathology was associated with a higher risk of postoperative mortality compared with a surgeon with subspeciality interest (OR: 1.38, p < 0.00001). In lower gastrointestinal (GI) pathologies, EL done by upper GI surgeons resulted in higher risk of mortality compared with lower GI surgeons (OR: 1.43, p < 0.00001). In upper GI pathologies, EL done by lower GI surgeons resulted in higher risk of mortality compared with upper GI surgeons (OR: 1.29, p = 0.05).

CONCLUSION

While confounding by indication cannot be excluded, level 2 evidence with moderate certainty suggests that trainee-led EL may not increase the risk of postoperative mortality but EL by a surgeon with subspeciality interest related to the pathology may reduce the risk of mortality.

摘要

目的

评估外科医生资历(实习外科医生与顾问外科医生)和外科医生专业兴趣对接受急诊剖腹手术(EL)患者术后死亡率的影响。

方法

系统评价根据 Cochrane 系统评价手册和 PRISMA 声明标准进行,并分别报告。我们评估了所有比较接受 EL 的患者在以下两种情况下术后死亡率风险的研究:(a)实习外科医生与顾问外科医生之间,以及(b)无相关病理专业兴趣的外科医生与有相关病理专业兴趣的外科医生之间。采用随机效应模型进行分析。使用 GRADE 系统评估证据的确定性。

结果

对 13 项研究中的 256844 名患者进行分析表明,实习外科医生主导的 EL 与顾问外科医生主导的 EL 在术后死亡率风险方面无差异(OR:0.76,p=0.12)。然而,与有相关病理专业兴趣的外科医生相比,无相关病理专业兴趣的外科医生进行 EL 与术后死亡率风险增加相关(OR:1.38,p<0.00001)。在胃肠道(GI)下病理中,上 GI 外科医生进行 EL 比下 GI 外科医生的死亡率风险更高(OR:1.43,p<0.00001)。在上 GI 病理中,下 GI 外科医生进行 EL 比上 GI 外科医生的死亡率风险更高(OR:1.29,p=0.05)。

结论

尽管不能排除混杂因素,但具有中等确定性的 2 级证据表明,实习外科医生主导的 EL 可能不会增加术后死亡率风险,但具有相关病理专业兴趣的外科医生进行 EL 可能会降低死亡率风险。

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