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美国 2009-2019 年严重心理困扰人群中大麻使用比例不成比例增加,以及与精神卫生服务使用的关联。

Disproportionate increase in cannabis use among people with serious psychological distress and associations with psychiatric service use in the United States, 2009-2019.

机构信息

Health Equity Research Lab, Cambridge Health Alliance, 1493 Cambridge Street, Cambridge, MA 02139, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

Health Equity Research Lab, Cambridge Health Alliance, 1493 Cambridge Street, Cambridge, MA 02139, USA; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

出版信息

Addict Behav. 2024 Oct;157:108095. doi: 10.1016/j.addbeh.2024.108095. Epub 2024 Jun 19.

Abstract

BACKGROUND

Cannabis use is on the rise, but it is unclear how use is changing among individuals with serious psychological distress (SPD) compared to the general population as well as what associations this may have with mental health service use.

METHODS

Retrospective cohort study using the National Survey on Drug Use and Health (NSDUH) 2009-19 public use files of 447,228 adults aged ≥ 18 years. Multivariable logistic regression and predictive margin methods were used to estimate linear time trends in any and greater-than-weekly levels of cannabis use by year and SPD status and rates of psychiatric hospitalization and outpatient mental health care.

FINDINGS

Rates of any and weekly-plus cannabis use increased similarly among individuals with SPD compared to those without from 200 to 2014 but more rapidly in SPD every year from 2015 to 2019 (p < 0.001). Among individuals with SPD, no use was associated with a 4.2 % probability of psychiatric hospitalization, significantly less than less-than-weekly (5.0 %, p = 0.037) and weekly-plus cannabis use (5.1 %, p = 0.028). For outpatient mental health care, no use was associated with a 27.4 % probability (95 % CI 26.7-28.1 %) of any outpatient care, significantly less than less than weekly use (32.6 % probability, p < 0.001) and weekly-plus use (29.9 % probability, p = 0.01).

CONCLUSIONS

Cannabis use is increasing more rapidly among individuals with SPD than the general population, and is associated with increased rates of psychiatric hospitalization and outpatient service use. These findings can inform policy makers looking to tailor regulations on advertising for cannabis and develop public health messaging on cannabis use by people with mental illness.

摘要

背景

大麻使用呈上升趋势,但尚不清楚与一般人群相比,患有严重心理困扰(SPD)的个体的使用情况如何变化,以及这可能与心理健康服务的使用有何关联。

方法

使用国家药物使用和健康调查(NSDUH)2009-19 年 447,228 名年龄≥18 岁的成年人公共使用文件进行回顾性队列研究。使用多变量逻辑回归和预测边际方法,按年和 SPD 状况以及精神病住院和门诊心理健康护理率,估计任何和每周以上大麻使用水平的线性时间趋势。

结果

从 200 年到 2014 年,与没有 SPD 的个体相比,患有 SPD 的个体的任何和每周以上大麻使用的比率都相似地增加,但从 2015 年到 2019 年,每年 SPD 的增加速度都更快(p<0.001)。在患有 SPD 的个体中,不使用大麻与精神病住院的概率为 4.2%,明显低于每周使用一次(5.0%,p=0.037)和每周以上使用(5.1%,p=0.028)。对于门诊心理健康护理,不使用大麻与任何门诊护理的概率(95%CI 26.7-28.1%)相关,明显低于每周使用一次(32.6%,p<0.001)和每周以上使用(29.9%,p=0.01)。

结论

与一般人群相比,患有 SPD 的个体中大麻的使用增加得更快,并且与精神病住院和门诊服务使用的增加率相关。这些发现可以为政策制定者提供信息,帮助他们针对大麻广告制定法规,并制定针对患有精神疾病的人使用大麻的公共卫生信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c01/11283347/0f0c1a314a8b/nihms-2006134-f0001.jpg

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