Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Integr Cancer Ther. 2024 Jan-Dec;23:15347354241261977. doi: 10.1177/15347354241261977.
To observe the clinical efficacy of Chinese herbal medicine combined with Liuzijue exercise on the physiological symptoms and quality of life (QoL) in postoperative patients with early-stage lung cancer.
One hundred and eighty-three lung cancer patients who underwent video-assisted thoracoscopic surgery (VATS) were categorize into either a traditional Chinese medicine treatment group (CM) or a control group (non-traditional Chinese medicine treatment, NC), among whom 73 underwent Chinese herbal medicine and Liuzijue therapy, while 110 underwent no comprehensive treatment with traditional Chinese medicine. The propensity score matching (PSM) method with a 1:2 ratio was used to balance the baseline characteristics and evaluate the efficacy of CM in improving postoperative symptoms and QoL.
Cough, dyspnea, chest pain, and fatigue were the most common clinical symptoms after VATS. Except for chest pain, they were all correlated with the scope of operation ( < .05). After PSM, 165 patients were identified in the matched cohort, and the covariates of gender, age, operative site, and scope of operation were balanced between the 2 groups ( > .05). In the domain of global health status, the improvement in QoL in CM was greater than that in NC (6.06 ± 15.83 vs -1.06 ± 14.68, = .005). In terms of symptoms, improvements in cough (1.69 ± 3.15 vs 0.38 ± 2.63, = .006), dyspnea during climbing stairs (-10.30 ± 16.82 vs -1.82 ± 17.97, = .004), and pain (-0.76 ± 1.32 vs -0.08 ± 1.31, = .002) in CM were better than in NC.
Comprehensive treatment with traditional Chinese medicine (TCM) can provide therapeutic benefits in physiological rehabilitation after VATS for cancer.
观察中药联合六字诀锻炼对早期肺癌术后患者生理症状和生活质量（QoL）的临床疗效。
将 183 例接受电视胸腔镜手术（VATS）的肺癌患者分为中药治疗组（CM）和对照组（非中药治疗，NC），其中 73 例采用中药和六字诀治疗，110 例未采用中药综合治疗。采用倾向性评分匹配（PSM）方法，1:2 比例平衡基线特征，评估 CM 改善术后症状和 QoL 的疗效。
VATS 后咳嗽、呼吸困难、胸痛和乏力是最常见的临床症状，除胸痛外，均与手术范围有关（ < .05）。PSM 后，匹配队列中确定了 165 例患者，2 组的性别、年龄、手术部位和手术范围的协变量均衡（ > .05）。在整体健康状况领域，CM 的 QoL 改善大于 NC（6.06 ± 15.83 与-1.06 ± 14.68， = .005）。在症状方面，CM 组的咳嗽（1.69 ± 3.15 与 0.38 ± 2.63， = .006）、爬楼梯时呼吸困难（-10.30 ± 16.82 与-1.82 ± 17.97， = .004）和疼痛（-0.76 ± 1.32 与-0.08 ± 1.31， = .002）的改善均优于 NC。
综合应用中药治疗可促进 VATS 后癌症患者生理康复。
