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竖脊肌平面阻滞在腹腔镜腹部手术中的镇痛效果:系统评价和荟萃分析。

Analgesia efficacy of erector spinae plane block in laparoscopic abdominal surgeries: a systemic review and meta-analysis.

机构信息

Department of Colorectal Surgery, Sengkang General Hospital.

Department of Anaesthesiology, Khoo Teck Phuat Hospital.

出版信息

Int J Surg. 2024 Jul 1;110(7):4393-4401. doi: 10.1097/JS9.0000000000001421.

Abstract

BACKGROUND

Multimodal analgesia is now widely practised to minimise postoperative opioid consumption while optimising pain control. The aim of this meta-analysis was to assess the analgesic efficacy of erector spinae plane block (ESPB) in patients undergoing laparoscopic abdominal surgeries. This will be determined by perioperative opioid consumption, subjective pain scores, and incidences of postoperative nausea and vomiting.

METHODS

The authors systemically searched electronic databases for randomised controlled trials (RCTs) published up to February 2023 comparing ESPB with other adjuvant analgesic techniques in laparoscopic abdominal surgeries. Nine randomised controlled trials encompassing 666 subjects were included in our study.

RESULTS

ESPB was shown to reduce postoperative opioid consumption [mean difference (MD) of -5.95 mg (95% CI: -8.86 to -3.04; P <0.0001); I2 =89%], intraoperative opioid consumption MD of -102.4 mcg (95% CI: -145.58 to -59.21; P <0.00001); I2 =39%, and incidence of nausea [RR 0.38 (95% CI: 0.25-0.60; P <0.0001); I2 =0%] and vomiting [RR 0.32 (95% CI: 0.17-0.63; P =0.0009); I2 =0%] in laparoscopic abdominal surgeries. Subgroup analysis on laparoscopic colorectal surgeries further showed reduction in postoperative pain scores MD of -0.68 (95% CI: -0.94 to -0.41); P <0.00001; I2 =0%].

CONCLUSIONS

This study concludes that ESPB is a valuable technique with proven efficacy to potentially promote faster postoperative recovery through optimising pain control while minimising opioid requirements.

摘要

背景

多模式镇痛目前广泛应用于最小化术后阿片类药物的消耗,同时优化疼痛控制。本荟萃分析的目的是评估竖脊肌平面阻滞(ESPB)在腹腔镜腹部手术患者中的镇痛效果。这将通过围手术期阿片类药物消耗、主观疼痛评分以及术后恶心和呕吐的发生率来确定。

方法

作者系统地检索了截至 2023 年 2 月比较 ESPB 与其他辅助镇痛技术在腹腔镜腹部手术中的随机对照试验(RCT)的电子数据库。我们的研究纳入了 9 项 RCT,共 666 名受试者。

结果

ESPB 可减少术后阿片类药物消耗[平均差值(MD)-5.95mg(95%置信区间:-8.86 至-3.04;P<0.0001);I2=89%]、术中阿片类药物消耗 MD-102.4μg(95%置信区间:-145.58 至-59.21;P<0.00001);I2=39%]和恶心发生率[RR 0.38(95%置信区间:0.25-0.60;P<0.0001);I2=0%]和呕吐[RR 0.32(95%置信区间:0.17-0.63;P=0.0009);I2=0%]的发生率腹腔镜腹部手术。腹腔镜结直肠手术的亚组分析进一步显示术后疼痛评分 MD 降低了-0.68(95%置信区间:-0.94 至-0.41);P<0.00001;I2=0%]。

结论

本研究得出结论,ESPB 是一种有效的技术,通过优化疼痛控制同时最小化阿片类药物需求,有可能促进更快的术后恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/852c/11254305/c5dd49135f5e/js9-110-4393-g001.jpg

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