基于植物的饮食指数与胆囊疾病的关联：来自 NHANES 的横断面研究。
Association between plant-based dietary index and gallstone disease: A cross sectional study from NHANES.
机构信息
Postgraduate Training Base of Air Force Medical Center, China Medical University, Beijing, China.
Department of Hepatobiliary Surgery, Air Force Medical Center, Air Force Medical University, Beijing, China.
出版信息
PLoS One. 2024 Jun 25;19(6):e0305822. doi: 10.1371/journal.pone.0305822. eCollection 2024.
BACKGROUND
The relationship between plant-based diets and gallstone disease has been debated. This study aimed to shed light on the association between plant-based dietary index and the risk of developing gallstone disease.
METHODS
Eligible participants were selected from National Health and Nutrition Examination Survey (NHANES) 2017-2020. Three plant-based diet indexes (PDI, healthy PDI, unhealthy PDI) were calculated using data from two NHANES 24-h dietary recall interviews. Restricted Cubic Spline and multivariate logistic regression were used to analyze the associations. Subgroup analysis was adopted to make the results more robust.
RESULTS
A total of 5673 eligible participants were analyzed. After adjusting for various confounding variables, uPDI was positively associated with gallstone disease (OR = 1.53, 95%CI: 1.02-2.29). No association was found between PDI/hPDI and gallstone disease (p > 0.05). The results of subgroup analysis did not show any positive association between uPDI and gallstones in specific groups.
CONCLUSION
Our study shows that the elevated uPDI are linked to a higher risk of gallstone disease.
背景
植物性饮食与胆石病之间的关系一直存在争议。本研究旨在探讨植物性饮食指数与胆石病发病风险之间的关系。
方法
从 2017-2020 年全国健康与营养调查（NHANES）中选择符合条件的参与者。使用两次 NHANES 24 小时膳食回顾访谈的数据计算三种植物性饮食指数（PDI、健康 PDI、不健康 PDI）。采用受限三次样条和多变量 logistic 回归分析关联。采用亚组分析使结果更加稳健。
结果
共分析了 5673 名符合条件的参与者。调整了各种混杂变量后，uPDI 与胆石病呈正相关（OR=1.53，95%CI：1.02-2.29）。PDI/hPDI 与胆石病之间无关联（p>0.05）。亚组分析结果显示，uPDI 与特定人群的胆石病之间没有任何正相关关系。
结论
我们的研究表明，升高的 uPDI 与更高的胆石病风险相关。
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