Student Research Committee, Department of Community Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
BMC Endocr Disord. 2023 May 16;23(1):109. doi: 10.1186/s12902-023-01358-7.
BACKGROUND: Metabolic syndrome (MetS) is a common chronic disease with several complications. Given that, studies on the association of plant-based diet indices (PDIs) with risk of MetS among adults with obesity, are limited, we aimed to examine the association between PDIs (including overall PDI, healthy PDI (hPDI), unhealthy PDI (uPDI)) and MetS in Iranian adults with obesity. METHODS: In Tabriz, Iran, a total of 347 adults between the ages of 20 and 50 participated in this cross-sectional research study. We created an overall PDI, hPDI, and uPDI from validated semi-quantitative food-frequency questionnaire (FFQ) data. To investigate the association between hPDI, overall PDI, uPDI, and MetS and its components, a binary logistic regression analysis was performed. RESULTS: The average age was 40.78 ± 9.23 years, and the average body mass index was 32.62 ± 4.80 kg/m. There was no significant association between overall PDI (OR: 0.87; 95% CI: 0.54-1.47), hPDI (OR: 0.82; 95% CI: 0.48-1.40), and uPDI (OR: 0.83; 95% CI: 0.87-2.46) with MetS, even after adjustment for confounders. Moreover, our findings showed that participants with the highest adherence to uPDI had a higher chance of hyperglycemia (OR: 2.50; 95% CI: 1.13-5.52). Also, this association was significant in the first (OR: 2.51; 95% CI: 1.04-6.04) and second (OR: 2.58; 95% CI: 1.05-6.33) models, after controlling for covariates. However, in both adjusted and crude models, we did not find a significant association between hPDI and PDI scores and MetS components such as high triglyceride, high waist circumference, low High-density lipoprotein cholesterol, raised blood pressure, and hyperglycemia. Moreover, those in the top tertile of uPDI had higher fasting blood sugar and insulin levels when compared with those in the first tertile, and subjects in the last tertile of hPDI compared with participants in the first tertile had lower weight, waist-to-hip ratio, and fat-free mass. CONCLUSION: We found a direct significant association between uPDI and odds of hyperglycemia in the whole population of study. Future large-scale, prospective studies on PDIs and the MetS are necessary to confirm these findings.
背景：代谢综合征（MetS）是一种常见的慢性疾病，伴有多种并发症。鉴于此，关于植物性饮食指数（PDI）与肥胖成年人代谢综合征风险之间的关联的研究有限，我们旨在研究伊朗肥胖成年人中 PDI（包括总体 PDI、健康 PDI（hPDI）、不健康 PDI（uPDI））与代谢综合征之间的关系。
方法：在伊朗大不里士，共有 347 名年龄在 20 至 50 岁之间的成年人参与了这项横断面研究。我们从经过验证的半定量食物频率问卷（FFQ）数据中创建了总体 PDI、hPDI 和 uPDI。为了研究 hPDI、总体 PDI、uPDI 与代谢综合征及其成分之间的关联，我们进行了二元逻辑回归分析。
结果：平均年龄为 40.78±9.23 岁，平均体重指数为 32.62±4.80kg/m。总体 PDI（OR：0.87；95%CI：0.54-1.47）、hPDI（OR：0.82；95%CI：0.48-1.40）和 uPDI（OR：0.83；95%CI：0.87-2.46）与代谢综合征之间没有显著关联，即使在调整了混杂因素后也是如此。此外，我们的研究结果表明，最高 uPDI 依从性的参与者发生高血糖的几率更高（OR：2.50；95%CI：1.13-5.52）。此外，在控制协变量后，这种关联在第一（OR：2.51；95%CI：1.04-6.04）和第二（OR：2.58；95%CI：1.05-6.33）模型中均具有统计学意义。然而，在调整和未调整模型中，我们均未发现 hPDI 和 PDI 评分与代谢综合征成分（如高甘油三酯、高腰围、低高密度脂蛋白胆固醇、高血压和高血糖）之间存在显著关联。此外，与第一三分位相比，uPDI 最高三分位的空腹血糖和胰岛素水平较高，而 hPDI 最后三分位的参与者的体重、腰臀比和去脂体重则较低。
结论：我们发现 uPDI 与研究人群中高血糖的几率之间存在直接显著关联。需要进行更大规模的前瞻性研究，以进一步证实 PDI 与代谢综合征之间的关系。
BMC Endocr Disord. 2023-5-16
Am J Health Behav. 2022-6-23
Metab Syndr Relat Disord. 2022-10
Am J Health Behav. 2021-11-15
Zotero 插件
