Meletiadis Arianna, Romano Angelo, Moroni Barbara, Di Nicola Matteo Riccardo, Montemurro Vittoria, Pitti Monica, Pezzolato Marzia, Bozzetta Elena, Sciuto Simona, Acutis Pier Luigi
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154 Turin, Italy.
Faculty of Veterinary Medicine, Department of Pathobiology, Pharmacology and Zoological Medicine, Wildlife Health Ghent, Ghent University, 9820 Merelbeke, Belgium.
Animals (Basel). 2024 Jun 7;14(12):1722. doi: 10.3390/ani14121722.
Reptiles are usually asymptomatic carriers of , with the manifestation of typical clinical signs of acute forms in adult and non-immunocompromised animals being considered exceptions. In the present case, an adult male corn snake () was found dead due to septic shock 48 h after consuming a feeder mouse purchased online. The snake's tissue samples and faeces were cultured for bacteria isolation. Microbiological examinations of the snake and mouse livers revealed the presence of . serovar Midway. A whole-genome analysis of these two isolates showed a high correlation between them: they belonged to the strain type ST-357 for the classic MLST scheme and to the strain type ST 171322 for the cgMLST scheme. Also, a virulence gene analysis revealed the presence of stdB and STM3026 genes. This report conveys a case of food-borne salmonellosis in a pet snake, transmitted from a feeder mouse, likely responsible for the snake's death due to septic shock. It highlights the relevance of feeder mice as a source of infections in snakes and the associated risks to human health.
爬行动物通常是沙门氏菌的无症状携带者，成年且无免疫功能低下的动物出现典型急性症状被视为例外情况。在本病例中，一条成年雄性玉米蛇（玉米锦蛇）在食用了网上购买的喂食小鼠48小时后，因感染性休克死亡。对蛇的组织样本和粪便进行细菌培养分离。对蛇和小鼠肝脏的微生物学检查发现存在沙门氏菌血清型Midway。对这两个分离株的全基因组分析显示它们之间有高度相关性：按照经典多位点序列分型方案，它们属于ST-357菌株类型；按照核心多位点序列分型方案，它们属于ST 171322菌株类型。此外，毒力基因分析显示存在stdB和STM3026基因。本报告传达了一例宠物蛇因食用喂食小鼠而感染食源性沙门氏菌病的病例，可能是导致蛇因感染性休克死亡的原因。它强调了喂食小鼠作为蛇类感染沙门氏菌的来源的相关性以及对人类健康的相关风险。
