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巴西南部圈养的响尾蛇沙门氏菌病致死病例的病理和微生物学研究结果。

Pathological and Microbiological Findings in Fatal Cases of Salmonellosis in Captive Bothrops Snakes in Southern Brazil.

机构信息

Setor de Patologia Veterinária, , Departamento de Patologia Clínica Veterinária, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Laboratório de Análises Clínicas Veterinárias, Departamento de Patologia Clínica Veterinária, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

出版信息

J Comp Pathol. 2021 Jul;186:7-12. doi: 10.1016/j.jcpa.2021.04.011. Epub 2021 May 31.

DOI:10.1016/j.jcpa.2021.04.011
PMID:34340807
Abstract

Salmonella spp. are gram-negative commensal bacteria of vertebrates, including reptiles. Infected snakes may be asymptomatic or manifest clinical disease and death, especially after stressful events. Salmonellosis was diagnosed in 10 captive snakes from the Bothrops genus. The most frequent changes were emaciation (8/10), fibrinonecrotic or granulomatous hepatitis (8/9), fibrinonecrotic or granulomatous enterocolitis (8/9), necrotic and heterophilic myocarditis (2/10), fibrinonecrotic or granulomatous pancreatitis (2/5), fibrinoheterophilic osteomyelitis (1/10), fibrinous and pyogranulomatous pericarditis (1/10) and granulomatous splenitis (1/6). Salmonella enterica was isolated from six cases. The subspecies identified were arizonae (3/6), diarizonae (1/6) and houtenae (1/6), in addition to the serotype Typhimurium (1/6). In cases without isolation, there was immunolabelling of Salmonella spp. in intestinal (3/4), hepatic (1/4) and cardiac (1/4) lesions.

摘要

沙门氏菌属是包括爬行动物在内的脊椎动物的革兰氏阴性共生菌。受感染的蛇可能无症状或表现出临床疾病和死亡,特别是在经历应激事件后。从 10 条 Bothrops 属的圈养蛇中诊断出沙门氏菌病。最常见的变化是消瘦(8/10)、纤维蛋白坏死或肉芽肿性肝炎(8/9)、纤维蛋白坏死或肉芽肿性肠炎(8/9)、坏死和异嗜性心肌炎(2/10)、纤维蛋白坏死或肉芽肿性胰腺炎(2/5)、纤维蛋白异嗜性骨髓炎(1/10)、纤维蛋白和化脓性心包炎(1/10)和肉芽肿性脾炎(1/6)。从 6 个病例中分离出肠炎沙门氏菌。鉴定的亚种有亚利桑那亚种(3/6)、迪阿里桑那亚种(1/6)和豪滕亚种(1/6),此外还有肠炎血清型(1/6)。在未分离出的病例中,肠道(3/4)、肝脏(1/4)和心脏(1/4)病变中存在沙门氏菌属的免疫标记。

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