Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, New Taipei City 23561, Taiwan.
Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11002, Taiwan.
Medicina (Kaunas). 2024 May 26;60(6):867. doi: 10.3390/medicina60060867.
Cafestol, a bioactive compound found in coffee, has attracted considerable attention due to its potential impact on cardiovascular health. This review aims to comprehensively explore the association between cafestol and cardiovascular diseases. We delve into the mechanisms through which cafestol influences lipid metabolism, inflammation, and endothelial function, all of which are pivotal in cardiovascular pathophysiology. Moreover, we meticulously analyze epidemiological studies and clinical trials to elucidate the relationship between cafestol and cardiovascular outcomes. Through a critical examination of existing literature, we aim to provide insights into the potential benefits and risks associated with cafestol concerning cardiovascular health.
咖啡醇,一种存在于咖啡中的生物活性化合物,因其对心血管健康的潜在影响而引起了广泛关注。本综述旨在全面探讨咖啡醇与心血管疾病之间的关联。我们深入研究了咖啡醇影响脂质代谢、炎症和内皮功能的机制,这些机制在心血管病理生理学中都至关重要。此外,我们还仔细分析了流行病学研究和临床试验,以阐明咖啡醇与心血管结局之间的关系。通过对现有文献的批判性评估,我们旨在深入了解咖啡醇对心血管健康的潜在益处和风险。