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多潘立酮治疗胃排空延迟患者的功能性消化不良。

Domperidone in the treatment of functional dyspepsia in patients with delayed gastric emptying.

作者信息

Bekhti A, Rutgeerts L

出版信息

Postgrad Med J. 1979;55 Suppl 1:30-2.

PMID:382151
Abstract

Forty patients who were suffering from chronic dyspepsia, diagnosed clinically and radiologically as being related to delayed gastric emptying, were treated with either domperidone or placebo in a double-blind trial. The trial lasted four weeks and the dose of domperidone was 10 mg orally t.d.s. before meals. The results showed that the drug markedly improved symptoms and that side effects were few, being recorded in one patient only, on active treatment. It is concluded that domperidone is a useful agent for the treatment of dyspepsia with retarded gastric emptying.

摘要

40例患有慢性消化不良的患者,经临床和放射学诊断为与胃排空延迟有关,在一项双盲试验中接受多潘立酮或安慰剂治疗。试验持续4周,多潘立酮的剂量为饭前口服10毫克,每日3次。结果表明,该药物显著改善了症状,且副作用很少,仅1例接受活性治疗的患者出现副作用。结论是,多潘立酮是治疗胃排空延迟性消化不良的有效药物。

相似文献

1
Domperidone in the treatment of functional dyspepsia in patients with delayed gastric emptying.多潘立酮治疗胃排空延迟患者的功能性消化不良。
Postgrad Med J. 1979;55 Suppl 1:30-2.
2
A double-blind crossover trial of domperidone in chronic postprandial dyspepsia.多潘立酮治疗慢性餐后消化不良的双盲交叉试验。
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Compatibility of high doses of both oral domperidone and neuroleptics in chronic psychotics.高剂量口服多潘立酮与抗精神病药在慢性精神病患者中的相容性。
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Comparative Efficacy of Various Pharmacological Interventions in the Treatment of Functional Dyspepsia: A Network Meta-Analysis.各种药物干预治疗功能性消化不良的疗效比较:网络荟萃分析。
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BMC Gastroenterol. 2017 Jun 26;17(1):83. doi: 10.1186/s12876-017-0639-0.
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ACG and CAG Clinical Guideline: Management of Dyspepsia.ACG 和 CAG 临床指南:消化不良的管理。
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Proton pump inhibitors for functional dyspepsia.用于功能性消化不良的质子泵抑制剂。
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Saudi Gastroenterology Association position statement on safety issues associated with the use of domperidone.沙特胃肠病学协会关于使用多潘立酮相关安全问题的立场声明。
Saudi J Gastroenterol. 2014 Sep-Oct;20(5):267-9. doi: 10.4103/1319-3767.141683.
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