Montes G, Cuello C, Gordillo G, Pelon W, Johnson W, Correa P
Cancer Lett. 1979 Oct;7(6):307-12. doi: 10.1016/s0304-3835(79)80058-0.
Gastric juice samples from patients of a rural area of the Colombian Andes at high risk to gastric cancer were tested for mutagenesis with Salmonella typhimurium strains TA100 and TA1538. Direct mutagenic effect was found in samples with detectable amounts of nitrite. This effect was not accountable by nitrite alone. Nitrite-negative samples from the same area and samples from the low-risk area of Cali were negative using the same mutagenesis assay.
对哥伦比亚安第斯山脉农村地区胃癌高风险患者的胃液样本，用鼠伤寒沙门氏菌TA100和TA1538菌株检测其致突变性。在检测到含有亚硝酸盐的样本中发现了直接诱变效应。这种效应不能仅由亚硝酸盐来解释。使用相同的诱变试验，来自同一地区的亚硝酸盐阴性样本以及来自卡利低风险地区的样本均为阴性。
